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Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance.
Published in:
Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 2, p. 669, doi. 10.1007/s00432-022-04416-0
By:
- Torlot, Lucien;
- Jarzab, Anna;
- Albert, Johanna;
- Pók-Udvari, Ágnes;
- Stahler, Arndt;
- Holch, Julian Walter;
- Gerlinger, Marco;
- Heinemann, Volker;
- Klauschen, Frederick;
- Kirchner, Thomas;
- Kumbrink, Jörg;
- Küster, Bernhard;
- Jung, Andreas
Publication type:
Article
Comparison of a coaxial versus non-coaxial liver biopsy technique in an oncological setting: diagnostic yield, complications and seeding risk.
Published in:
European Radiology, 2020, v. 30, n. 12, p. 6702, doi. 10.1007/s00330-020-07038-7
By:
- Fotiadis, Nicos;
- De Paepe, Katja N.;
- Bonne, Lawrence;
- Khan, Nasir;
- Riddell, Angela;
- Turner, Nicholas;
- Starling, Naureen;
- Gerlinger, Marco;
- Rao, Sheela;
- Chau, Ian;
- Cunningham, David;
- Koh, Dow-Mu
Publication type:
Article
Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas.
Published in:
Journal of Pathology, 2013, v. 231, n. 4, p. 424, doi. 10.1002/path.4284
By:
- Gerlinger, Marco;
- Quezada, Sergio A;
- Peggs, Karl S;
- Furness, Andrew JS;
- Fisher, Rosalie;
- Marafioti, Teresa;
- Shende, Vishvesh H;
- McGranahan, Nicholas;
- Rowan, Andrew J;
- Hazell, Steven;
- Hamm, David;
- Robins, Harlan S;
- Pickering, Lisa;
- Gore, Martin;
- Nicol, David L;
- Larkin, James;
- Swanton, Charles
Publication type:
Article
Parallel evolution of tumour subclones mimics diversity between tumours.
Published in:
Journal of Pathology, 2013, v. 230, n. 4, p. 356, doi. 10.1002/path.4214
By:
- Martinez, Pierre;
- Birkbak, Nicolai Juul;
- Gerlinger, Marco;
- McGranahan, Nicholas;
- Burrell, Rebecca A;
- Rowan, Andrew J;
- Joshi, Tejal;
- Fisher, Rosalie;
- Larkin, James;
- Szallasi, Zoltan;
- Swanton, Charles
Publication type:
Article
Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target.
Published in:
Journal of Pathology, 2012, v. 227, n. 2, p. 146, doi. 10.1002/path.4006
By:
- Gerlinger, Marco;
- Santos, Claudio R;
- Spencer-Dene, Bradley;
- Martinez, Pierre;
- Endesfelder, David;
- Burrell, Rebecca A;
- Vetter, Marcus;
- Jiang, Ming;
- Saunders, Rebecca E;
- Kelly, Gavin;
- Dykema, Karl;
- Rioux-Leclercq, Nathalie;
- Stamp, Gordon;
- Patard, Jean Jacques;
- Larkin, James;
- Howell, Michael;
- Swanton, Charles
Publication type:
Article
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing.
Published in:
Nature Genetics, 2014, v. 46, n. 3, p. 225, doi. 10.1038/ng.2891
By:
- Gerlinger, Marco;
- Horswell, Stuart;
- Larkin, James;
- Rowan, Andrew J;
- Salm, Max P;
- Varela, Ignacio;
- Fisher, Rosalie;
- McGranahan, Nicholas;
- Matthews, Nicholas;
- Santos, Claudio R;
- Martinez, Pierre;
- Phillimore, Benjamin;
- Begum, Sharmin;
- Rabinowitz, Adam;
- Spencer-Dene, Bradley;
- Gulati, Sakshi;
- Bates, Paul A;
- Stamp, Gordon;
- Pickering, Lisa;
- Gore, Martin
Publication type:
Article
Circulating Tumour DNA Sequencing Identifies a Genetic Resistance-Gap in Colorectal Cancers with Acquired Resistance to EGFR-Antibodies and Chemotherapy.
Published in:
Cancers, 2020, v. 12, n. 12, p. 3736, doi. 10.3390/cancers12123736
By:
- Knebel, Franciele H.;
- Barber, Louise J.;
- Newey, Alice;
- Kleftogiannis, Dimitrios;
- Woolston, Andrew;
- Griffiths, Beatrice;
- Fenwick, Kerry;
- Bettoni, Fabiana;
- Ribeiro, Maurício Fernando Silva Almeida;
- da Fonseca, Leonardo;
- Costa, Frederico;
- Capareli, Fernanda Cunha;
- Hoff, Paulo M.;
- Sabbaga, Jorge;
- Camargo, Anamaria A.;
- Gerlinger, Marco
Publication type:
Article
Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma.
Published in:
Cancers, 2019, v. 11, n. 5, p. 736, doi. 10.3390/cancers11050736
By:
- Davidson, Michael;
- Barber, Louise J.;
- Woolston, Andrew;
- Cafferkey, Catherine;
- Mansukhani, Sonia;
- Griffiths, Beatrice;
- Moorcraft, Sing-Yu;
- Rana, Isma;
- Begum, Ruwaida;
- Assiotis, Ioannis;
- Matthews, Nik;
- Rao, Sheela;
- Watkins, David;
- Chau, Ian;
- Cunningham, David;
- Starling, Naureen;
- Gerlinger, Marco
Publication type:
Article
Effect of perioperative FLOT versus ECF/ECX on short-term outcomes after surgery for resectable oesophagogastric adenocarcinoma: propensity score-matched study.
Published in:
BJS Open, 2022, v. 6, n. 1, p. 1, doi. 10.1093/bjsopen/zrac003
By:
- Moussa, Osama;
- Bhogal, Ricky Harminder;
- Malietzis, George;
- Fribbens, Charlotte;
- Starling, Naureen;
- Gerlinger, Marco;
- Watkins, David;
- Chau, Ian;
- Rao, Sheela;
- Cunningham, David;
- Allum, William H.;
- Chaudry, Asif;
- Kumar, Sacheen
Publication type:
Article
Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution.
Published in:
Genome Biology, 2014, v. 15, n. 8, p. 1, doi. 10.1186/s13059-014-0433-z
By:
- Fisher, Rosalie;
- Horswell, Stuart;
- Rowan, Andrew;
- Salm, Maximilian P.;
- de Bruin, Elza C.;
- Gulati, Sakshi;
- McGranahan, Nicholas;
- Stares, Mark;
- Gerlinger, Marco;
- Varela, Ignacio;
- Crockford, Andrew;
- Favero, Francesco;
- Quidville, Virginie;
- André, Fabrice;
- Navas, Carolina;
- Grönroos, Eva;
- Nicol, David;
- Hazell, Steve;
- Hrouda, David;
- O'Brien, Tim
Publication type:
Article
The promise of circulating tumor cell analysis in cancer management.
Published in:
Genome Biology, 2014, v. 15, n. 8, p. 448, doi. 10.1186/s13059-014-0448-5
By:
- Mateo, Joaquin;
- Gerlinger, Marco;
- Rodrigues, Daniel Nava;
- de Bono, Johann S
Publication type:
Article
Efficacy and Cardiotoxic Safety Profile of Raltitrexed in Fluoropyrimidines-Pretreated or High-Risk Cardiac Patients With GI Malignancies: Large Single-Center Experience.
Published in:
2019
By:
- Khan, Khurum;
- Rane, Jayant K.;
- Cunningham, David;
- Rao, Sheela;
- Watkins, David;
- Starling, Naureen;
- Kalaitzaki, Eleftheria;
- Forster, Martin;
- Braconi, Chiara;
- Valeri, Nicola;
- Gerlinger, Marco;
- Chau, Ian
Publication type:
journal article
Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study.
Published in:
2018
By:
- Kayhanian, Hamzeh;
- Goode, Emily;
- Sclafani, Francesco;
- Ang, Joo Ern;
- Gerlinger, Marco;
- de Castro, David Gonzalez;
- Shepherd, Scott;
- Peckitt, Clare;
- Rao, Sheela;
- Watkins, David;
- Chau, Ian;
- Cunningham, David;
- Starling, Naureen;
- Gonzalez de Castro, David
Publication type:
journal article
Intratumor Heterogeneity: Seeing the Wood for the Trees.
Published in:
Science Translational Medicine, 2012, v. 4, n. 127, p. 1, doi. 10.1126/scitranslmed.3003854
By:
- Yap, Timothy A.;
- Gerlinger, Marco;
- Futreal, P. Andrew;
- Pusztai, Lajos;
- Swanton, Charles
Publication type:
Article
Identifying key questions in the ecology and evolution of cancer.
Published in:
Evolutionary Applications, 2021, v. 14, n. 4, p. 877, doi. 10.1111/eva.13190
By:
- Dujon, Antoine M.;
- Aktipis, Athena;
- Alix‐Panabières, Catherine;
- Amend, Sarah R.;
- Boddy, Amy M.;
- Brown, Joel S.;
- Capp, Jean‐Pascal;
- DeGregori, James;
- Ewald, Paul;
- Gatenby, Robert;
- Gerlinger, Marco;
- Giraudeau, Mathieu;
- Hamede, Rodrigo K.;
- Hansen, Elsa;
- Kareva, Irina;
- Maley, Carlo C.;
- Marusyk, Andriy;
- McGranahan, Nicholas;
- Metzger, Michael J.;
- Nedelcu, Aurora M.
Publication type:
Article
Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets.
Published in:
Genome Medicine, 2010, v. 2, n. 8, p. 1, doi. 10.1186/gm174
By:
- Swanton, Charles;
- Larkin, James M.;
- Gerlinger, Marco;
- Eklund, Aron C.;
- Howell, Michael;
- Stamp, Gordon;
- Downward, Julian;
- Gore, Martin;
- Futreal, P. Andrew;
- Escudier, Bernard;
- Andre, Fabrice;
- Albiges, Laurence;
- Beuselinck, Benoit;
- Oudard, Stephane;
- Hoffmann, Jens;
- Gyorffy, Balázs;
- Torrance, Chris J.;
- Boehme, Karen A.;
- Volkmer, Hansjuergen;
- Toschi, Luisella
Publication type:
Article
Heterogeneous response and progression patterns reveal phenotypic heterogeneity of tyrosine kinase inhibitor response in metastatic renal cell carcinoma.
Published in:
BMC Medicine, 2016, v. 14, p. 1, doi. 10.1186/s12916-016-0729-9
By:
- Crusz, Shanthini M.;
- Yen Zhi Tang;
- Sarker, Shah-Jalal;
- Prevoo, Warner;
- Kiyani, Irfan;
- Beltran, Luis;
- Peters, John;
- Sahdev, Anju;
- Bex, Axel;
- Powles, Thomas;
- Gerlinger, Marco
Publication type:
Article
Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes.
Published in:
2021
By:
- Challoner, Benjamin R;
- Loga, Katharina von;
- Woolston, Andrew;
- Griffiths, Beatrice;
- Sivamanoharan, Nanna;
- Semiannikova, Maria;
- Newey, Alice;
- Barber, Louise J;
- Mansfield, David;
- Hewitt, Lindsay C;
- Saito, Yuichi;
- Davarzani, Naser;
- Starling, Naureen;
- Melcher, Alan;
- Grabsch, Heike I;
- Gerlinger, Marco;
- von Loga, Katharina
Publication type:
journal article
Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes.
Published in:
2022
By:
- Somarelli, Jason A.;
- DeGregori, James;
- Gerlinger, Marco;
- Heng, Henry H.;
- Marusyk, Andriy;
- Welch, Danny R.;
- Laukien, Frank H.
Publication type:
journal article
Author Correction: Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer.
Published in:
2020
By:
- von Loga, Katharina;
- Woolston, Andrew;
- Punta, Marco;
- Barber, Louise J.;
- Griffiths, Beatrice;
- Semiannikova, Maria;
- Spain, Georgia;
- Challoner, Benjamin;
- Fenwick, Kerry;
- Simon, Ronald;
- Marx, Andreas;
- Sauter, Guido;
- Lise, Stefano;
- Matthews, Nik;
- Gerlinger, Marco
Publication type:
Correction Notice
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13915-7
By:
- von Loga, Katharina;
- Woolston, Andrew;
- Punta, Marco;
- Barber, Louise J.;
- Griffiths, Beatrice;
- Semiannikova, Maria;
- Spain, Georgia;
- Challoner, Benjamin;
- Fenwick, Kerry;
- Simon, Ronald;
- Marx, Andreas;
- Sauter, Guido;
- Lise, Stefano;
- Matthews, Nik;
- Gerlinger, Marco
Publication type:
Article

Found: 21