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- Title
Pulmonary alveolar proteinosis in a patient with Behcet's disease.
- Authors
UCHIYAMA, Michihiro; NAGAO, Tsuyoshi; HATTORI, Aritoshi; FUJII, Tatsuya; ICHIWATA, Toshio; NAKATA, Koh; TANI, Kenzaburo; HAYASHI, Takuya
- Abstract
Secondary pulmonary alveolar proteinosis (PAP) has been described in several clinical settings that can be grouped into three main categories: infections of the lung; haematological malignancies and other conditions that alter the patient's immune status; and exposure to inhaled chemicals and minerals. Recent studies reported that anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) antibody was present in the serum of patients with idiopathic PAP but not in patients with secondary PAP or in normal subjects. The present report describes the interesting case of a patient with Behcet's disease and PAP. The absence of anti-GM-CSF antibodies in this patient suggested a diagnosis of secondary PAP.
- Subjects
BEHCET'S disease; PULMONARY alveoli; PATIENTS; GRANULOCYTES; MACROPHAGES; IMMUNOGLOBULINS
- Publication
Respirology, 2009, Vol 14, Issue 2, p305
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/j.1440-1843.2008.01450.x