We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Posterior cortical atrophy: a rare form of dementia with in vivo evidence of amyloid-beta accumulation.
- Authors
Tenovuo O; Kemppainen N; Aalto S; Någren K; Rinne JO; Tenovuo, Olli; Kemppainen, Nina; Aalto, Sargo; Någren, Kjell; Rinne, Juha O
- Abstract
Posterior cortical atrophy (PCA) is a rare form of degenerative dementia, which is characterized by progressive atrophy of occipital and parietal cortical areas. It usually manifests as increasing difficulties of visuoperceptive abilities. Later on, memory and other cognitive functions are involved. Various pathologies have been associated with clinical PCA presentation, but most of the patients with autopsy have had Alzheimer-type pathology. Thus, PCA has been considered to be a rare form of Alzheimer-type dementia with unusual pathological distribution. Here we describe a patient who had a typical clinical course for this syndrome and who showed a positive accumulation of amyloid-beta in posterior areas studied with positron emission tomography.
- Publication
Journal of Alzheimer's Disease, 2008, Vol 15, Issue 3, p351
- ISSN
1387-2877
- Publication type
journal article
- DOI
10.3233/jad-2008-15301