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- Title
Safety Profile of Ambulatory Prostatic Artery Embolization after a Significant Learning Curve: Update on Adverse Events.
- Authors
Amouyal, Gregory; Tournier, Louis; De Margerie-Mellon, Constance; Pachev, Atanas; Assouline, Jessica; Bouda, Damien; De Bazelaire, Cédric; Marques, Florent; Le Strat, Solenne; Desgrandchamps, François; De Kerviler, Eric
- Abstract
Background: to report the safety of outpatient prostatic artery embolization (PAE) after a significant learning curve. Methods: a retrospective bi-institutional study was conducted between June 2018 and April 2022 on 311 consecutive patients, with a mean age of 69 years ± 9.8 (47–102), treated by outpatient PAE. Indications included lower urinary tract symptoms, acute urinary retention, and hematuria. When needed, 3D-imaging and/or coil protection of extra-prostatic supplies were performed to avoid non-target embolization. Adverse events were monitored at 1-, 6-, and 12-month follow-ups. Results: bilateral PAE was achieved in 305/311 (98.1%). Mean dose area product/fluoroscopy times were 16,408.3 ± 12,078.9 (2959–81,608) μGy.m2/36.3 ± 1.7 (11–97) minutes. Coil protection was performed on 67/311 (21.5%) patients in 78 vesical, penile, or rectal supplies. Embolization-related adverse events varied between 0 and 2.6%, access-site adverse events between 0 and 18%, and were all minor. There was no major event. Conclusion: outpatient PAE performed after achieving a significant learning curve may lead to a decreased and low rate of adverse events. Experience in arterial anatomy and coil protection may play a role in safety, but the necessity of the latter in some patterns may need confirmation by additional studies in randomized designs.
- Subjects
URINARY organs; RETENTION of urine; ARTERIES; PROSTATE; PROSTATE hypertrophy; PENIS curvatures
- Publication
Journal of Personalized Medicine, 2022, Vol 12, Issue 8, p1261
- ISSN
2075-4426
- Publication type
Article
- DOI
10.3390/jpm12081261