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- Title
Problem of signal contamination in interhemispheric dual-sided subdural electrodes.
- Authors
Nune, George; Winawer, Jonathan; Rauschecker, Andreas M.; Dastjerdi, Mohammad; Foster, Brett L.; Wandell, Brian; Parvizi, Josef
- Abstract
Dual-sided subdural electrodes are used in the localization and lateralization of seizure-onset zones when the area of interest is within the interhemispheric fissure. We designed the current study to test the validity of the assumption that each side of the dual-sided electrodes records from the hemisphere it faces. We recorded with dual-sided strip and grid electrodes implanted in the occipital interhemispheric space in two patients with nonoccipital epilepsy during two visual stimulation tasks in which subjects were presented with visual stimuli in the ipsilateral or contralateral visual hemifields. Our findings show substantial contamination of recordings from the opposite hemisphere. Although, as expected, electrodes recording through the falx record faintly from the contralateral cortical surface, they unexpectedly pick up strong signals from the cortex behind them. Therefore, we conclude that these electrodes should not be used for lateralization of the origin of epileptic activity or evoked responses.
- Subjects
CORPUS callosum; ELECTRODES; CEREBRAL dominance; SEIZURES (Medicine); EPILEPSY surgery; VISUAL perception; STIMULUS &; response (Biology)
- Publication
Epilepsia (Series 4), 2011, Vol 52, Issue 11, pe176
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2011.03284.x