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Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies.
Published in:
2017
By:
- Maiko Ono;
- Naruhiko Sahara;
- Katsushi Kumata;
- Bin Ji;
- Ruiqing Ni;
- Shunsuke Koga;
- Dickson, Dennis W.;
- Trojanowski, John Q.;
- Lee, Virginia M-Y.;
- Mari Yoshida;
- Isao Hozumi;
- Yasumasa Yoshiyama;
- van Swieten, John C.;
- Nordberg, Agneta;
- Tetsuya Suhara;
- Ming-Rong Zhang;
- Makoto Higuchi;
- Ono, Maiko;
- Sahara, Naruhiko;
- Kumata, Katsushi
Publication type:
journal article
Clinical and Pathological Features of FTDP‐17 with MAPT p.K298_H299insQ Mutation.
Published in:
Movement Disorders Clinical Practice, 2024, v. 11, n. 6, p. 720, doi. 10.1002/mdc3.14042
By:
- Morino, Hiroyuki;
- Kurashige, Takashi;
- Matsuda, Yukiko;
- Ono, Maiko;
- Sahara, Naruhiko;
- Miyasaka, Tomohiro;
- Soeda, Yoshiyuki;
- Shimada, Hitoshi;
- Yamazaki, Yu;
- Takahashi, Tetsuya;
- Izumi, Yuishin;
- Ito, Hidefumi;
- Maruyama, Hirofumi;
- Higuchi, Makoto;
- Arihiro, Koji;
- Suhara, Tetsuya;
- Takashima, Akihiko;
- Kawakami, Hideshi
Publication type:
Article
IC‐P‐082: TAU AND ALPHA‐SYNUCLEIN SELECTIVE BINDING COMPOUNDS DERIVED FROM APRINOIA THERAPEUTIC'S PM‐PBB3 BINDING‐SITE FOCUSED COMPOUND COLLECTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P71, doi. 10.1016/j.jalz.2018.06.2146
By:
- Tempest, Paul;
- Ono, Maiko;
- Higuchi, Makogto;
- Shimada, Hitoshi;
- Suhara, Tetsuya;
- Tai, Chin Yin;
- Tamagnan, Gilles;
- Carroll, Vincent;
- Alagille, David;
- Barret, Olivier;
- Marek, Ken;
- Jang, Ming-Kuei
Publication type:
Article
Altered brain energy metabolism related to astrocytes in tauopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059834
By:
- Hirata, Kosei;
- Matsuoka, Kiwamu;
- Tagai, Kenji;
- Endo, Hironobu;
- Kokubo, Naomi;
- Tatebe, Harutsugu;
- Zhang, Hong;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Ono, Maiko;
- Obata, Takayuki;
- Kawamura, Kazunori;
- Zhang, Ming‐Rong;
- Shimada, Hitoshi;
- Tokuda, Takahiko;
- Yokota, Takanori;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
PROGRESS TOWARDS AN A‐SYNUCLEIN PET TRACER.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.063036
By:
- Tempest, Paul;
- Tai, Chin‐Yin;
- Ono, Maiko;
- Skaddan, Marc B;
- Wilcox, Kyle C;
- Reed, Aimee;
- Vaidyanathan, Srirajan;
- Christoffersen, Claus T;
- Kallunki, Pekka;
- Bang‐Andersen, Benny;
- Margolin, Richard A;
- Kao, Tzu‐Huei;
- Higuchi, Makoto;
- Jang, Ming‐Kuei
Publication type:
Article
PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.063028
By:
- Tempest, Paul;
- Lin, Yih‐Shyan;
- Tai, Chin‐Yin;
- Ono, Maiko;
- Russell, David S;
- Sandiego, Christine M;
- Carroll, Vincent;
- Gunn, Roger N;
- Margolin, Richard A;
- Higuchi, Makoto;
- Jang, Ming‐Kuei
Publication type:
Article
PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.063025
By:
- Tempest, Paul;
- Lin, Yih‐Shyan;
- Tai, Chin‐Yin;
- Ono, Maiko;
- Russell, David S;
- Sandiego, Christine M;
- Gunn, Roger N;
- Carroll, Vincent;
- Margolin, Richard A;
- Kao, Tzu‐Huei;
- Higuchi, Makoto;
- Jang, Ming‐Kuei
Publication type:
Article
Activation of Nav1.1 ameliorates tau pathology and brain atrophy in a mouse model of tauopathy: Nonhuman/Target identification and validation studies: Tau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038201
By:
- Sampei, Kazuaki;
- Seki, Chie;
- Takuwa, Hiroyuki;
- Maeda, Jun;
- Ono, Maiko;
- Tokunaga, Masaki;
- Shimojo, Masafumi;
- Honda, Shigeyuki;
- Kimura, Taeko;
- Ishikawa, Taizo;
- Kudo, Takehiro;
- Takado, Yuhei;
- Sahara, Naruhiko;
- Higuchi, Makoto
Publication type:
Article
Tau‐induced brain atrophy and neuroinflammation accelerated by low‐protein diet and decelerated by selected essential amino acids in a murine model of tauopathies: Molecular and cell biology/neurodegeneration and neuroprotection.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037539
By:
- Takado, Yuhei;
- Sato, Hideaki;
- Tsukamoto‐Yasui, Masako;
- Minatohara, Keiichiro;
- Takahashi, Manami;
- Urushihata, Takuya;
- Takuwa, Hiroyuki;
- Ono, Maiko;
- Maeda, Jun;
- Sahara, Naruhiko;
- Aoki, Ichio;
- Toyoda, Sakiko;
- Karakawa, Sachise;
- Isokawa, Muneki;
- Kawasaki, Noriko;
- Ueno, Satoko;
- Kanda, Mayuka;
- Nishimura, Mai;
- Suzuki, Katsuya;
- Mitsui, Akira
Publication type:
Article
P2‐382: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P749, doi. 10.1016/j.jalz.2019.06.2789
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
P1‐400: TAU AND ALPHA‐SYNUCLEIN SELECTIVE BINDING COMPOUNDS DERIVED FROM APRINOIA THERAPEUTIC'S PM‐PBB3 BINDING‐SITE FOCUSED COMPOUND COLLECTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P455, doi. 10.1016/j.jalz.2018.06.408
By:
- Tempest, Paul;
- Ono, Maiko;
- Higuchi, Makogto;
- Shimada, Hitoshi;
- Suhara, Tetsuya;
- Zhang, Ming-Rong;
- Tai, Chin Yin;
- Carroll, Vincent;
- Tamagnan, Gilles;
- Marek, Ken;
- Barret, Olivier;
- Alagille, David;
- Jang, Ming-Kuei
Publication type:
Article
P1‐125: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P318, doi. 10.1016/j.jalz.2018.06.128
By:
- Shimada, Hitoshi;
- Ono, Maiko;
- Tagai, Kenji;
- Kubota, Manabu;
- Kitamura, Soichiro;
- Takuwa, Hiroyuki;
- Seki, Chie;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Yamamoto, Naoyoshi;
- Sano, Yasunori;
- Takado, Yuhei;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Marek, Kenneth
Publication type:
Article
IC‐P‐217: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P177, doi. 10.1016/j.jalz.2018.06.2284
By:
- Shimada, Hitoshi;
- Ono, Maiko;
- Tagai, Kenji;
- Kubota, Manabu;
- Kitamura, Soichiro;
- Takuwa, Hiroyuki;
- Seki, Chie;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Yamamoto, Naoyoshi;
- Sano, Yasunori;
- Takado, Yuhei;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Marek, Kenneth
Publication type:
Article
IC‐P‐082: TAU AND ALPHA‐SYNUCLEIN SELECTIVE BINDING COMPOUNDS DERIVED FROM APRINOIA THERAPEUTIC'S PM‐PBB3 BINDING‐SITE FOCUSED COMPOUND COLLECTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P71, doi. 10.1016/j.jalz.2018.06.2146
By:
- Tempest, Paul;
- Ono, Maiko;
- Higuchi, Makogto;
- Shimada, Hitoshi;
- Suhara, Tetsuya;
- Tai, Chin Yin;
- Tamagnan, Gilles;
- Carroll, Vincent;
- Alagille, David;
- Barret, Olivier;
- Marek, Ken;
- Jang, Ming-Kuei
Publication type:
Article
Front Cover: Design, Synthesis, and Biological Evaluation of Novel Fluorescent Probes Targeting the 18‐kDa Translocator Protein (12/2021).
Published in:
ChemMedChem, 2021, v. 16, n. 12, p. 1833, doi. 10.1002/cmdc.202100379
By:
- Wongso, Hendris;
- Yamasaki, Tomoteru;
- Kumata, Katsushi;
- Ono, Maiko;
- Higuchi, Makoto;
- Zhang, Ming‐Rong;
- Fulham, Michael J.;
- Katsifis, Andrew;
- Keller, Paul A.
Publication type:
Article
Design, Synthesis, and Biological Evaluation of Novel Fluorescent Probes Targeting the 18‐kDa Translocator Protein.
Published in:
ChemMedChem, 2021, v. 16, n. 12, p. 1902, doi. 10.1002/cmdc.202000984
By:
- Wongso, Hendris;
- Yamasaki, Tomoteru;
- Kumata, Katsushi;
- Ono, Maiko;
- Higuchi, Makoto;
- Zhang, Ming‐Rong;
- Fulham, Michael J.;
- Katsifis, Andrew;
- Keller, Paul A.
Publication type:
Article
A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains.
Published in:
EMBO Journal, 2021, v. 40, n. 22, p. 1, doi. 10.15252/embj.2021107757
By:
- Shimojo, Masafumi;
- Ono, Maiko;
- Takuwa, Hiroyuki;
- Mimura, Koki;
- Nagai, Yuji;
- Fujinaga, Masayuki;
- Kikuchi, Tatsuya;
- Okada, Maki;
- Seki, Chie;
- Tokunaga, Masaki;
- Maeda, Jun;
- Takado, Yuhei;
- Takahashi, Manami;
- Minamihisamatsu, Takeharu;
- Zhang, Ming‐Rong;
- Tomita, Yutaka;
- Suzuki, Norihiro;
- Maximov, Anton;
- Suhara, Tetsuya;
- Minamimoto, Takafumi
Publication type:
Article
FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P146, doi. 10.1016/j.jalz.2017.06.2573
By:
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- Ono, Maiko;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Takahata, Keisuke;
- Moriguchi, Sho;
- Kubota, Manabu;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Seki, Chie;
- Hirano, Shigeki;
- Shinotoh, Hitoshi;
- Sahara, Naruhiko;
- Tempest, Paul;
- Tamagnan, Gilles;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Zhang, Ming-Rong
Publication type:
Article
VISUALIZATION OF MICROGLIAL RESPONSE TO TAU-INDUCED NEURODEGENERATION IN A MODEL OF TAUOPATHY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1292, doi. 10.1016/j.jalz.2017.06.1953
By:
- Sahara, Naruhiko;
- Jun, Maeda;
- Ishikawa, Ai;
- Ono, Maiko;
- Takuwa, Hiroyuki;
- Shimojo, Masafumi;
- Minamihisamatsu, Takeharu;
- Tokunaga, Masaki;
- Uchida, Shouko;
- Matsumoto, Izumi;
- Ji, Bin;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1104, doi. 10.1016/j.jalz.2017.06.1594
By:
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- ONO, Maiko;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Takahata, Keisuke;
- Moriguchi, Sho;
- Kubota, Manabu;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Seki, Chie;
- Hirano, Shigeki;
- Shinotoh, Hitoshi;
- Sahara, Naruhiko;
- Tempest, Paul;
- Tamagnan, Gilles;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Zhang, Ming-Rong
Publication type:
Article
NOVEL COMPOUNDS FOR PET IMAGING OF AD AND NON-AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P148, doi. 10.1016/j.jalz.2017.06.2577
By:
- Tempest, Paul;
- Jang, Ming-Kuei;
- Higuchi, Makoto;
- Ono, Maiko;
- Tang, Xiubo;
- Cai, Dongmei;
- Zhang, Yi;
- Liu, Rock;
- Liu, Rongfeng
Publication type:
Article
[11C]PBB3 PET VISUALIZES TAU AGGREGATES IN PATIENTS WITH FTDP-17 MAPT GENE MUTATION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P135, doi. 10.1016/j.jalz.2016.06.217
By:
- Shinotoh, Hitoshi;
- Sahara, Naruhiko;
- Shimada, Hitoshi;
- Ikeuchi, Takeshi;
- Shunske, Koga;
- Strogonsky, Audrey J.;
- Nishioka, Kenya;
- Hanyu, Haruo;
- van Swieten, John C.;
- Ono, Maiko;
- Kimura, Yasuyuki;
- Hirano, Shigeki;
- Ishii, Kenji;
- Zhang, Ming-Rong;
- Trojanowski, John Q.;
- M-Y Lee, Virginia;
- Dickson, Dennis W.;
- Wszolek, Zbigniew;
- Hattori, Nobutaka;
- Higuchi, Makoto
Publication type:
Article
INVESTIGATING THE LINK BETWEEN PATHOLOGICAL TAU ACCUMULATION, NEUROINFLAMMATION AND BRAIN ATROPHY IN A MODEL OF TAUOPATHY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P530, doi. 10.1016/j.jalz.2016.06.1037
By:
- Sahara, Naruhiko;
- Ishikawa, Ai;
- Tokunaga, Masaki;
- Minamihisamatsu, Takeharu;
- Shimojo, Masafumi;
- Ono, Maiko;
- Uchida, Shouko;
- Matsumoto, Izumi;
- Takuwa, Hiroyuki;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
RADIOLIGAND BINDING ASSAYS FOR COMPARISON OF TAU PET PROBES, PBB3 AND T807, IN DETECTION OF TAU PATHOLOGIES IN ALZHEIMER'S DISEASE AND PSP BRAINS, AND NEUROTOXIC TAU SPECIES IN A TRANSGENIC MOUSE MODEL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P725, doi. 10.1016/j.jalz.2016.06.1426
By:
- Ni, Ruiqing;
- Ji, Bin;
- Ono, Maiko;
- Sahara, Naruhiko;
- Aoki, Ichio;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Utility of tau imaging probe pbb3 on a mouse model of tauopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P284, doi. 10.1016/j.jalz.2015.07.383
By:
- Sahara, Naruhiko;
- Ishikawa, Ai;
- Tokunaga, Masaki;
- Minamihisamatsu, Takeharu;
- Maeda, Jun;
- Ono, Maiko;
- Uchida, Shouko;
- Matsumoto, Izumi;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Selective autophagy in neurons and its involvement in tau pathogenesis
Published in:
2012
By:
- Ono, Maiko;
- Ji, Bin;
- Tokunaga, Masaki;
- Minamihisamatsu, Takeharu;
- Maruyama, Masahiro;
- Maeda, Jun;
- Komatsu, Masaaki;
- Ishii, Tetsuro;
- Warabi, Eiji;
- Yanagawa, Toru;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Abstract
Significance of 18-kDa translocator protein in monitoring and regulating microglial response to Aβ amyloidosis: An in vivo PET study of microglia-implanted mouse models
Published in:
2010
By:
- Ji, Bin;
- Sawada, Makoto;
- Hattori, Satoko;
- Maruyama, Masahiro;
- Maeda, Jun;
- Ono, Maiko;
- Okauchi, Takashi;
- Suzuki, Hiromi;
- Zhang, Ming-Rong;
- Higuchi, Makoto;
- Suhara, Tetsuya
Publication type:
Abstract
In vivo optical and PET detections of fibrillar tau lesions in a mouse model of tauopathies
Published in:
2009
By:
- Maruyama, Masahiro;
- Maeda, Jun;
- Ji, Bin;
- Zhang, Ming-Rong;
- Okauchi, Takashi;
- Ono, Maiko;
- Hattori, Satoko;
- Trojanowski, John Q.;
- Lee, Virginia M.-Y.;
- Fukumura, Toshimitsu;
- Higuchi, Makoto;
- Suhara, Tetsuya
Publication type:
Abstract
In vivo optical and PET detections of fibrillar tau lesions in a mouse model of tauopathies
Published in:
2009
By:
- Maruyama, Masahiro;
- Maeda, Jun;
- Ji, Bin;
- Zhang, Ming-Rong;
- Okauchi, Takashi;
- Ono, Maiko;
- Hattori, Satoko;
- Trojanowski, John Q.;
- Lee., Virginia M.-Y.;
- Fukumura, Toshimitsu;
- Higuchi, Makoto;
- Suhara, Tetsuya
Publication type:
Abstract
Low-dose total-body carbon-ion irradiations induce early transcriptional alteration without late Alzheimer's disease-like pathogenesis and memory impairment in mice.
Published in:
Journal of Neuroscience Research, 2014, v. 92, n. 7, p. 915, doi. 10.1002/jnr.23363
By:
- Wang, Bing;
- Tanaka, Kaoru;
- Ji, Bin;
- Ono, Maiko;
- Fang, Yaqun;
- Ninomiya, Yasuharu;
- Maruyama, Kouichi;
- Izumi‐Nakajima, Nakako;
- Begum, Nasrin;
- Higuchi, Makoto;
- Fujimori, Akira;
- Uehara, Yoshihiko;
- Nakajima, Tetsuo;
- Suhara, Tetsuya;
- Nenoi, Mitsuru
Publication type:
Article
Astrotactin 2 (ASTN2) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems.
Published in:
Journal of Neurochemistry, 2023, v. 165, n. 2, p. 211, doi. 10.1111/jnc.15790
By:
- Ito, Takahiro;
- Yoshida, Mikio;
- Aida, Tomomi;
- Kushima, Itaru;
- Hiramatsu, Yuka;
- Ono, Maiko;
- Yoshimi, Akira;
- Tanaka, Kohichi;
- Ozaki, Norio;
- Noda, Yukihiro
Publication type:
Article
Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies.
Published in:
Journal of Neuroscience, 2008, v. 28, n. 47, p. 12255, doi. 10.1523/JNEUROSCI.2312-08.2008
By:
- Ji, Bin;
- Maeda, Jun;
- Sawada, Makoto;
- Ono, Maiko;
- Okauchi, Takashi;
- Inaji, Motoki;
- Ming-Rong Zhang;
- Suzuki, Kazutoshi;
- Ando, Kiyoshi;
- Staufenbiel, Matthias;
- Trojanowski, John Q.;
- Lee, Virginia M. Y.;
- Higuchi, Makoto;
- Suhara, Tetsuya
Publication type:
Article
Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 41, p. 10957, doi. 10.1523/JNEUROSCI.0673-07.2007
By:
- Maeda, Jun;
- Bin Ji;
- Irie, Toshiaki;
- Tomiyama, Takami;
- Maruyama, Masahiro;
- Okauchi, Takashi;
- Staufenbiel, Matthias;
- Iwata, Nobuhisa;
- Ono, Maiko;
- Saido, Takaomi C.;
- Suzuki, Kazutoshi;
- Mori, Hiroshi;
- Higuchi, Makoto;
- Suhara, Tetsuya
Publication type:
Article
MRS-measured glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 1, p. 197, doi. 10.1177/0271678X211045449
By:
- Takado, Yuhei;
- Takuwa, Hiroyuki;
- Sampei, Kazuaki;
- Urushihata, Takuya;
- Takahashi, Manami;
- Shimojo, Masafumi;
- Uchida, Shoko;
- Nitta, Nobuhiro;
- Shibata, Sayaka;
- Nagashima, Keisuke;
- Ochi, Yoshihiro;
- Ono, Maiko;
- Maeda, Jun;
- Tomita, Yutaka;
- Sahara, Naruhiko;
- Near, Jamie;
- Aoki, Ichio;
- Shibata, Kazuhisa;
- Higuchi, Makoto
Publication type:
Article
Detection of Alzheimer's disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 8, p. 2076, doi. 10.1177/0271678X21992457
By:
- Ji, Bin;
- Ono, Maiko;
- Yamasaki, Tomoteru;
- Fujinaga, Masayuki;
- Zhang, Ming-Rong;
- Seki, Chie;
- Aoki, Ichio;
- Kito, Seiji;
- Sawada, Makoto;
- Suhara, Tetsuya;
- Sahara, Naruhiko;
- Higuchi, Makoto
Publication type:
Article
Mechanistic involvement of the calpain-calpastatin system in Alzheimer neuropathology.
Published in:
FASEB Journal, 2012, v. 26, n. 3, p. 1204, doi. 10.1096/fj.11-187740
By:
- Higuchi, Makoto;
- Iwata, Nobuhisa;
- Matsuba, Yukio;
- Takano, Jiro;
- Suemoto, Takahiro;
- Maeda, Jun;
- Ji, Bin;
- Ono, Maiko;
- Staufenbiel, Matthias;
- Suhara, Tetsuya;
- Saido, Takaomi C.
Publication type:
Article
Imaging of amyloid deposition in human brain using positron emission tomography and [F]FACT: comparison with [C]PIB.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 4, p. 745, doi. 10.1007/s00259-013-2620-7
By:
- Ito, Hiroshi;
- Shinotoh, Hitoshi;
- Shimada, Hitoshi;
- Miyoshi, Michie;
- Yanai, Kazuhiko;
- Okamura, Nobuyuki;
- Takano, Harumasa;
- Takahashi, Hidehiko;
- Arakawa, Ryosuke;
- Kodaka, Fumitoshi;
- Ono, Maiko;
- Eguchi, Yoko;
- Higuchi, Makoto;
- Fukumura, Toshimitsu;
- Suhara, Tetsuya
Publication type:
Article
Acute abdominal pain due to atypical bilateral adrenal infarction in acute myeloid leukemia with alterations related to myelodysplasia: A case report.
Published in:
2023
By:
- Hirata, Risa;
- Tago, Masaki;
- Yamashita, Shun;
- Yamamoto, Satsuki;
- Yaita, Shizuka;
- Hirakawa, Yuka;
- Ono, Maiko;
- Yamashita, Shu‐ichi
Publication type:
Case Study
A human PET study of [C]HMS011, a potential radioligand for AMPA receptors.
Published in:
EJNMMI Research, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13550-017-0313-0
By:
- Takahata, Keisuke;
- Kimura, Yasuyuki;
- Seki, Chie;
- Tokunaga, Masaki;
- Ichise, Masanori;
- Kawamura, Kazunori;
- Ono, Maiko;
- Kitamura, Soichiro;
- Kubota, Manabu;
- Moriguchi, Sho;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Niwa, Fumitoshi;
- Endo, Hironobu;
- Nagashima, Tomohisa;
- Ikoma, Yoko;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Comparative In Vitro and In Vivo Quantifications of Pathologic Tau Deposits and Their Association with Neurodegeneration in Tauopathy Mouse Models.
Published in:
Journal of Nuclear Medicine, 2018, v. 59, n. 6, p. 960, doi. 10.2967/jnumed.117.201632
By:
- Ruiqing Ni;
- Bin Ji;
- Maiko Ono;
- Naruhiko Sahara;
- Ming-Rong Zhang;
- Ichio Aoki;
- Nordberg, Agneta;
- Tetsuya Suhara;
- Makoto Higuchi
Publication type:
Article
In Vivo SPECT Imaging of Amyloid-P Deposition with Radioiodinated Imidazo[1,2-α]Pyridine Derivative DRM106 in a Mouse Model of Alzheimer's Disease.
Published in:
Journal of Nuclear Medicine, 2015, v. 56, n. 1, p. 120, doi. 10.2967/jnumed.114.146944
By:
- Chun-Jen Chen;
- Kazunori Bando;
- Hiroki Ashino;
- Kazumi Taguchi;
- Hideaki Shiraishi;
- Keiji Shima;
- Osuke Fujimoto;
- Chiemi Kitamura;
- Satoshi Matsushima;
- Keisuke Uchida;
- Yuto Nakahara;
- Hiroyuki Kasahara;
- Takao Minamizawa;
- Cheng Jiang;
- Ming-Rong Zhang;
- Maiko Ono;
- Masaki Tokunaga;
- Tetsuya Suhara;
- Makoto Higuchi;
- Kazutaka Yamada
Publication type:
Article
Radiosynthesis, Photoisomerization, Biodistribution, and Metabolite Analysis of 11C-PBB3 as a Clinically Useful PET Probe for Imaging of Tau Pathology.
Published in:
Journal of Nuclear Medicine, 2014, v. 55, n. 9, p. 1532, doi. 10.2967/jnumed.114.139550
By:
- Hiroki Hashimoto;
- Kazunori Kawamura;
- Nobuyuki Igarashi;
- Makoto Takei;
- Tomoya Fujishiro;
- Yoshiharu Aihara;
- Satoshi Shiomi;
- Masatoshi Muto;
- Takehito Ito;
- Kenji Furutsuka;
- Tomoteru Yamasaki;
- Joji Yui;
- Lin Xie;
- Maiko Ono;
- Akiko Hatori;
- Kazuyoshi Nemoto;
- Tetsuya Suhara;
- Makoto Higuchi;
- Ming-Rong Zhang
Publication type:
Article
Distinct binding of amyloid imaging ligands to unique amyloid-β deposited in the presubiculum of Alzheimer's disease.
Published in:
Journal of Neurochemistry, 2015, v. 135, n. 5, p. 859, doi. 10.1111/jnc.13293
By:
- Ji, Bin;
- Chen, Chun‐Jen;
- Bando, Kazunori;
- Ashino, Hiroki;
- Shiraishi, Hideaki;
- Sano, Hiroaki;
- Kasahara, Hiroyuki;
- Minamizawa, Takao;
- Yamada, Kazutaka;
- Ono, Maiko;
- Zhang, Ming‐Rong;
- Seki, Chie;
- Farde, Lars;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Total body 100-mGy X-irradiation does not induce Alzheimer's disease-like pathogenesis or memory impairment in mice.
Published in:
Journal of Radiation Research, 2014, v. 55, n. 1, p. 84, doi. 10.1093/jrr/rrt096
By:
- Wang, Bing;
- Tanaka, Kaoru;
- Ji, Bin;
- Ono, Maiko;
- Fang, Yaqun;
- Ninomiya, Yasuharu;
- Maruyama, Kouichi;
- Izumi-Nakajima, Nakako;
- Begum, Nasrin;
- Higuchi, Makoto;
- Fujimori, Akira;
- Uehara, Yoshihiko;
- Nakajima, Tetsuo;
- Suhara, Tetsuya;
- Ono, Tetsuya;
- Nenoi, Mitsuru
Publication type:
Article
The characteristics of a good clinical teacher as perceived by resident physicians in Japan: a qualitative study.
Published in:
BMC Medical Education, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1472-6920-13-100
By:
- Makoto Kikukawa;
- Hiromi Nabeta;
- Maiko Ono;
- Sei Emura;
- Yasutomo Oda;
- Shunzo Koizumi;
- Takanobu Sakemi
Publication type:
Article
The most requested factors in clinical skills exams for evaluating novice physicians: an internet-based survey of the general public in Japan.
Published in:
BMC Medical Education, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1472-6920-13-74
By:
- Otaki, Junji;
- Nagata-Kobayashi, Shizuko;
- Takayashiki, Ayumi;
- Ono, Maiko;
- Fukushi, Motoharu;
- Matsumura, Shinji
Publication type:
Article
Comparison of the peripheral blood leukocyte population between Japanese Black and Holstein calves.
Published in:
Animal Science Journal, 2011, v. 82, n. 1, p. 93, doi. 10.1111/j.1740-0929.2010.00833.x
By:
- OHTSUKA, Hiromichi;
- ONO, Maiko;
- SARUYAMA, Yumi;
- MUKAI, Machiko;
- KOHIRUIMAKI, Masayuki;
- KAWAMURA, Seiichi
Publication type:
Article
Japanese people's view of an ideal primary-care physician: a qualitative study.
Published in:
Asia Pacific Family Medicine, 2005, v. 4, p. 1
By:
- Ono, Maiko;
- Shinozuka, Masaya;
- Matsumura, Shinji;
- Takahashi, Miyako;
- Green, Joseph
Publication type:
Article

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