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- Title
Lung nodule volumetry: segmentation algorithms within the same software package cannot be used interchangeably.
- Authors
Ashraf H; de Hoop B; Shaker SB; Dirksen A; Bach KS; Hansen H; Prokop M; Pedersen JH; Ashraf, H; de Hoop, B; Shaker, S B; Dirksen, A; Bach, K S; Hansen, H; Prokop, M; Pedersen, J H
- Abstract
<bold>Objective: </bold>We examined the reproducibility of lung nodule volumetry software that offers three different volumetry algorithms.<bold>Methods: </bold>In a lung cancer screening trial, 188 baseline nodules >5 mm were identified. Including follow-ups, these nodules formed a study-set of 545 nodules. Nodules were independently double read by two readers using commercially available volumetry software. The software offers readers three different analysing algorithms. We compared the inter-observer variability of nodule volumetry when the readers used the same and different algorithms.<bold>Results: </bold>Both readers were able to correctly segment and measure 72% of nodules. In 80% of these cases, the readers chose the same algorithm. When readers used the same algorithm, exactly the same volume was measured in 50% of readings and a difference of >25% was observed in 4%. When the readers used different algorithms, 83% of measurements showed a difference of >25%.<bold>Conclusion: </bold>Modern volumetric software failed to correctly segment a high number of screen detected nodules. While choosing a different algorithm can yield better segmentation of a lung nodule, reproducibility of volumetric measurements deteriorates substantially when different algorithms were used. It is crucial even in the same software package to choose identical parameters for follow-up.
- Publication
European Radiology, 2010, Vol 20, Issue 8, p1878
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-010-1749-z