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- Title
Comparative clinical evaluation of xenograft (Cerabone) versus allograft combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects.
- Authors
Mitra, Suhina; Kamath, Deepa G.; Shetty, Nishmitha D.; Natarajan, Srikant
- Abstract
Aim: The present study aims to evaluate the efficacy of naturally-derived bovine hydroxyapatite (Cerabone) versus demineralized freeze-dried bone allograft both combined with platelet-rich fibrin for treatment of grade II mandibular furcation defects. Method: This clinical study included 20 systemically healthy patients, with grade II mandibular furcation defects, performed over 6 months. Control group comprised of open flap debridement + demineralized freeze-dried bone allograft + platelet-rich fibrin and test group comprised of open flap debridement + Cerabone + platelet-rich fibrin. Clinical parameters included: Plaque index, Modified Sulcular bleeding index, Vertical probing pocket depth, Horizontal probing depth, Probing clinical attachment level, Radiographic furcation depth, and radiographic bone fill percentage. Results: Both groups showed satisfactory bone regeneration and improvement in clinical parameters. The test group exhibited greater reduction in vertical probing pocket depth, horizontal probing depth, and higher radiographic bone fill percentage when compared to control group, although these findings were not statistically significant. Conclusion: Both bone grafts were equally effective in treatment of grade II furcation defects. Further long-term studies are required to explore their maximum regenerative potential.
- Subjects
HYDROXYAPATITE; TOOTH demineralization; XENOGRAFTS; HOMOGRAFTS; SAMPLE size (Statistics); DEBRIDEMENT; MANDIBLE; PERIODONTAL disease; HEALTH outcome assessment; POSTOPERATIVE care; TREATMENT effectiveness; RANDOMIZED controlled trials; COMPARATIVE studies; T-test (Statistics); DESCRIPTIVE statistics; STATISTICAL sampling; BONE regeneration; DATA analysis software; PLATELET-rich fibrin; LONGITUDINAL method; EVALUATION
- Publication
Acta Marisiensis. Seria Medica, 2023, Vol 69, Issue 2, p113
- ISSN
2668-7755
- Publication type
Article
- DOI
10.2478/amma-2023-0016