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- Title
Usefulness of a Non-Streptavidin Bead Technology to Overcome Biotin Interference: Proof of Principle with 25-OH Vitamin D, TSH, and FT4.
- Authors
Favresse, Julien; Bayart, Jean-Louis; Burlacu, Maria-Cristina; Maiter, Dominique; Dogné, Jean-Michel; Douxfils, Jonathan; Gruson, Damien
- Abstract
The article discusses a study which showed that the BioT-Filter filter device from QUALIblood SA was able to remove biotin with an efficiency of 95.99 percent from serum samples containing elevated biotin concentrations. Topics include the role of biotin interferences in avoiding misleading diagnoses and potential adverse consequences for patients, finding on the utilization of neutralization methods, and recommendation on the validation of approaches to assess or eliminate biotin interference.
- Subjects
FILTERS &; filtration; BIOTIN; SERUM; BODY fluids; MEDICAL equipment
- Publication
Journal of Applied Laboratory Medicine, 2021, Vol 6, Issue 4, p1072
- ISSN
2475-7241
- Publication type
Article
- DOI
10.1093/jalm/jfaa203