We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Larger Lateral Prefrontal Cortex Volume Predicts Better Exercise Adherence Among Older Women: Evidence From Two Exercise Training Studies.
- Authors
Best, John R.; Chiu, Bryan K.; Hall, Peter A.; Liu-Ambrose, Teresa
- Abstract
<bold>Background: </bold>Recent research has suggested an important role of lateral prefrontal cortex (lPFC) in consistent implementation of positive health behaviors and avoidance of negative health behaviors.<bold>Methods: </bold>We examined whether gray matter volume in the lPFC prospectively predicts exercise class attendance among older women (n = 122) who underwent either a 52-week or 26-week exercise training intervention. Structural magnetic resonance imaging determined gray matter volume at baseline.<bold>Results: </bold>Independent of intracranial volume, age, education, body composition, mobility, depressive symptoms, and general cognitive functioning, larger lPFC volume predicted greater exercise class attendance (all p values < .05). Follow-up whole-brain analyses further confirmed that regions in the lPFC-especially the left middle frontal gyrus (p < .005)-predicted future exercise adherence as well as identified other regions, especially in the insula and temporal cortex, that predicted exercise adherence.<bold>Conclusions: </bold>These findings suggest that sustained engagement in exercise training might rely in part on functions of the lPFC and that lPFC volume might be a reasonable proxy for such functions.
- Subjects
PREFRONTAL cortex; NEUROSCIENCES; HEALTH of older women; OLDER women; MENTAL health of older women; EXERCISE adherence; CONDUCT of life; COMPARATIVE studies; EXERCISE; FRONTAL lobe; LONGITUDINAL method; MAGNETIC resonance imaging; RESEARCH methodology; MEDICAL cooperation; PATIENT compliance; RESEARCH; EVALUATION research; RANDOMIZED controlled trials; GRAY matter (Nerve tissue)
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2017, Vol 72, Issue 6, p804
- ISSN
1079-5006
- Publication type
journal article
- DOI
10.1093/gerona/glx043