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- Title
Vitamin D during pregnancy and the neurodevelopment of the child: systematic review.
- Authors
Villalobos, Marcela; Tous, Monica; Canals, Josefa; Arija, Victoria
- Abstract
Background: A deficiency of vitamin D during pregnancy has a negative impact on maternal-infant health. Objective: To evaluate the effect of vitamin D status during pregnancy on offspring neurodevelopmental outcomes. Selection of studies: We explored studies that linked maternal vit amin D status with offspring neurodevelopmental outcomes. The studies selected were idendfied by systematically reviewing the scientific literature published in PubMed/MEDLINE, Scopus and Cochrane until January 2018. The quality of the studies was evaluated using the NewcastleOttawa scale. Results: 164 studies were identified and reviewed for selection. This systematic review, which comprises eleven studies (ten of a high methodological quality and one moderate), shows that mothers with vitamin D lev els <50 nmol/L during pregnancy had offspring with poorer mental, mo tor and language development compared to mothers with concentrations ≥50 nmol/L. Conclusion: There is still not enough scientific evidence to confirm the reladonship between prenatal vitamin D deficiency and off spring neurodevelopmental outcomes. However, recent data suggest a detrimental effect on the mental, motor and language development of offspring.
- Subjects
VITAMIN D deficiency; PREGNANCY complications; NEURAL development; INFANT development; INFANT health; MATERNAL health
- Publication
Anales de Psicología, 2019, Vol 35, Issue 3, p389
- ISSN
0212-9728
- Publication type
Article
- DOI
10.6018/analesps.35.3.326411