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- Title
内镜黏膜下剥离术和挖除术治疗上消化道肿瘤的疗效及安全性分析.
- Authors
陆启峰; 王双平; 代子艳; 陈保刚; 周亚柏; 柏婷婷
- Abstract
To analyze the efficacy and safety of upper gastrointestinal tumor treated by endoscopic submucosal dissection (ESD) and endoscopic submucosal excavation (ESE). Clinical data of 68 hospitalized patients with upper gastrointestinal tumor who underwent ESD or ESE in our hospital from January 2017 to April 2019 were collected, such as basic diseases, the size, operation time, complete resection rate and complication. According to the Logistic regression equation analysis, the risk factors for the complications of perforation were analyzed. The tumors of 64 cases (94.12%) of patients were en-bloc resected, and the average tumor size was (16.98± 8.29 mm). Pathological results showed that high grade intraepithelial neoplasia was the most, 15 cases (22.06%) in the lesion of esophagus. The top three were gastric body, gastric fundus and gastric antrum in gastric lesions, there were 18 cases (26.47%), 16 cases (23.53%) and 12 cases (17.65%), respectively. Pathological results showed that stromal tumor was the most (36.76%). Complications occurred in 11 cases (16.18%), included 4 cases (5.88%) of delayed bleeding (all of them were treated successfully by endoscopic hemostasis therapy), and 8 patients (11.76%) with perforation (all of them were successfully treated by coagulation hemostasis and hemoclip), including 1 patient with perforation and delayed bleeding. Lesion diameter (≥ 25 mm, P=0.036) and lesion locating at the gastric fundus (P=0.015) were the independent risk factors for perforation in ESD or ESE. ESD and ESE are safe and effective technique for upper gastrointestinal tumor. However, lesion diameter and lesion locating at the gastric fundus should be paid attention as they are the risk factors for perforation.
- Subjects
ENDOSCOPIC hemostasis; GASTROINTESTINAL tumors; LOGISTIC regression analysis; HOSPITAL patients; HEMOSTASIS; ESOPHAGUS; PANCREATIC intraepithelial neoplasia
- Publication
Progress in Modern Biomedicine, 2019, Vol 19, Issue 17, p3356
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2019.17.033