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- Title
Vitamin D deficiency in Korean children: prevalence, risk factors, and the relationship with parathyroid hormone levels.
- Authors
In Hyuk Chung; Hae Jung Kim; Sochung Chung; Eun-Gyong Yoo
- Abstract
Purpose: This study was performed to investigate the relationship between serum vitamin D and parathyroid hormone (PTH) levels as well as to describe the prevalence and the risk factors of vitamin D deficiency (VDD) in Korean children. Methods: Participants were 1,212 children aged 4 to 15 years, who visited Bundang CHA Medical Center (located at 37ºN) between March 2012 and February 2013. Overweight was defined as body mass index≥85th percentile. Participants were divided into 4 age groups and 2 seasonal groups. VDD was defined by serum 25-hydroxyvitamin D (25OHD) <20 ng/mL. Results: The level of 25OHD was significantly lower in overweight group than in normal weight group (17.1±5.1 ng/mL vs. 19.1±6.1 ng/mL, P<0.001). Winter-spring season (odds ratio [OR], 4.46; 95% confidence interval [CI], 3.45--5.77), older age group (OR, 1.60; 95% CI, 1.36--1.88), and overweight (OR, 2.21; 95% CI, 1.62--3.01) were independently related with VDD. The PTH levels were significantly higher in VDD group compared to vitamin D insufficiency and sufficiency group (P<0.001). In normal weight children, 25OHD (β=--0.007, P<0.001) and ionized calcium (β=--0.594, P=0.007) were independently related with PTH, however, these associations were not significant in overweight children. Conclusion: VDD is very common in Korean children and its prevalence increases in winter-spring season, in overweight children and in older age groups. Further investigation on the vitamin D and PTH metabolism according to adiposity is required.
- Subjects
VITAMIN D deficiency; DISEASE prevalence; DISEASE risk factors; PARATHYROID hormone; BODY mass index; CHILDHOOD obesity
- Publication
Annals of Pediatric Endocrinology & Metabolism, 2014, Vol 19, Issue 2, p86
- ISSN
2287-1012
- Publication type
Article
- DOI
10.6065/apem.2014.19.2.86