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- Title
Thermo-Search: Lifestyle and Thermostability Analysis.
- Authors
Farias, Savio T.; van der Linden, Marx G.; Rêgo, Thais G.; Araújo, Demétrius A.M.; Bonato, Maria Christina M.
- Abstract
Thermo-search is an online web tool for the analysis of proteomes and individual proteins according to the ratio of two couplets of preferred and avoided amino acids in hyperthermophiles, thermophiles and mesophiles. It displays the ratio between glutamic acid plus lysine (E+K) and glutamine plus histidine (Q+H), which is higher in thermophilic proteomes and thermostable proteins than in mesophilic proteomes and thermo labile proteins. Thermo-search allows a rapid screen of the CRM database for thermostable proteins in their functional categories and a visualization of the (E+K)/(Q+H) average ratio between organisms, allowing a comparison of their lifestyles.
- Subjects
AMINO acids; ORGANIC acids; PROTEOMICS; GLUTAMIC acid; BIOLOGY
- Publication
In Silico Biology, 2004, Vol 4, Issue 3, p377
- ISSN
1386-6338
- Publication type
Article