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- Title
Impact of metabolic syndrome on the viability of human spermatozoa: a cross-sectional descriptive study in men from infertile couples.
- Authors
Le, Minh Tam; Nguyen, Hiep Tuyet Thi; Dang, Hong Nhan Thi; Nguyen, Thai Thanh Thi; Van Nguyen, Trung; Nguyen, Quoc Huy Vu
- Abstract
Background: A direct association between metabolic syndrome (MetS) and sperm production/function has been proposed. In this cross-sectional study, we aimed to determine the impact of MetS on sperm survival. Men from infertile couples treated at Hue University Hospital, Vietnam, were enrolled in this study, which spanned the October 2018 to October 2020 period. The general characteristics of the patients, including body mass index (BMI), waist-to-hip ratio (WHR), the levels of different biochemicals, and semen parameters were determined, and sperm survival tests (SSTs) were performed. The modified National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III for the Asian population was used for MetS diagnosis. Results: Men with an abnormal waist circumference (≥ 90 cm) showed a higher rate of abnormal SST results (30.1% vs. 16.7%, p = 0.012). The frequency of abnormal SST results in patients with MetS (72.3%) was significantly higher than that in individuals without MetS (53.4%) (p = 0.02). Furthermore, the percentage of abnormal SST results in patients with MetS and with BMI ≥ 23 was significantly higher than those in individuals without MetS (77.1% vs. 55.2%, p = 0.03). Weak negative correlations were also observed between the patients' age and the SST results. Conclusion: Sperm viability was lower in men with MetS. We also observed that age and BMI were independent factors associated with abnormal SST.
- Subjects
VIETNAM; MALE infertility; METABOLIC syndrome; SPERMATOZOA; WAIST-hip ratio; CROSS-sectional method; BODY mass index
- Publication
Basic & Clinical Andrology, 2021, Vol 31, Issue 1, p1
- ISSN
2051-4190
- Publication type
Article
- DOI
10.1186/s12610-021-00142-8