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- Title
Unraveling the Multifaceted Role of the Golgi Apparatus: Insights into Neuronal Plasticity, Development, Neurogenesis, Alzheimer's Disease, and SARS-CoV-2 Interactions.
- Authors
Toader, Corneliu; Eva, Lucian; Covache-Busuioc, Razvan-Adrian; Costin, Horia Petre; Glavan, Luca-Andrei; Corlatescu, Antonio Daniel; Ciurea, Alexandru Vlad
- Abstract
This article critically evaluates the multifunctional role of the Golgi apparatus within neurological paradigms. We succinctly highlight its influence on neuronal plasticity, development, and the vital trafficking and sorting mechanisms for proteins and lipids. The discourse further navigates to its regulatory prominence in neurogenesis and its implications in Alzheimer's Disease pathogenesis. The emerging nexus between the Golgi apparatus and SARS-CoV-2 underscores its potential in viral replication processes. This consolidation accentuates the Golgi apparatus's centrality in neurobiology and its intersections with both neurodegenerative and viral pathologies. In essence, understanding the Golgi's multifaceted functions harbors profound implications for future therapeutic innovations in neurological and viral afflictions.
- Subjects
GOLGI apparatus; NEUROPLASTICITY; ALZHEIMER'S disease; NEUROGENESIS; SARS-CoV-2
- Publication
Brain Sciences (2076-3425), 2023, Vol 13, Issue 10, p1363
- ISSN
2076-3425
- Publication type
Article
- DOI
10.3390/brainsci13101363