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- Title
SEROLOGICAL HETEROGENEITY OF THE IgM COMPONENTS OF MIXED (MONOCLONAL JgM- POLYCLONAL IgG) CRYOGLOBULINS.
- Authors
MacKenzie, M. R.; Goldberg, L. S.; Barnett, E. V.; Fudenberg, H. H.
- Abstract
The article presents a study, which determines whether the Immunoglobulin M (IgM) components of mixed cryoglobulins vary in antigenic specificity. For this purpose, the authors studied the serological interactions in three test systems of the IgM components isolated from seven different cryoglobulinaemic sera. The results of this study indicate that serological specificity may vary from one mixed cryoglobulin to another and that the monoclonal IgM components of different mixed cryoglobulins represent a heterologous group of antiglobulins.
- Subjects
IMMUNOGLOBULIN M; CRYOGLOBULINS; AUTOANTIBODIES; SERUM; IMMUNOSPECIFICITY; IMMUNOGLOBULIN idiotypes; CRYOGLOBULINEMIA
- Publication
Clinical & Experimental Immunology, 1968, Vol 3, Issue 9, p931
- ISSN
0009-9104
- Publication type
Article