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- Title
Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis.
- Authors
Ham, Henk-Jan van den; De Jager, Wilco; Bijlsma, Johannes W. J.; Prakken, Berent J.; De Boer, Rob J.
- Abstract
Objectives. With the introduction of high-throughput biomarker measurements, traditional analysis of these markers is increasingly difficult. Using samples from a diverse group of patients, we tested the applicability of cluster analysis to these data. Using this method, we aim to visualize some of the patterns specific to certain disease groups. In particular, we focus on juvenile idiopathic arthritis (JIA), a multifactorial autoimmune disorder that ultimately leads to chronic inflammation of the joints.
- Subjects
CYTOKINES; JUVENILE idiopathic arthritis; CLUSTER analysis (Statistics); INFLAMMATION; BIOMARKERS
- Publication
Rheumatology, 2009, Vol 48, Issue 8, p899
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kep125