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- Title
Novel mutation in cutaneous oncocytoma identified by next‐generation sequencing.
- Authors
Smith, Shane D. B.; Ma, Charles; Lichy, Jack; Chen, Wen; Nava, Victor E.
- Abstract
NGS identified a somatic mutation of EGFR and long noncoding RNA EGFR antisense RNA 1 (lnc EGFR-AS1). We document a case report of cutaneous oncocytoma with a novel mutation of uncertain significance affecting EGFR and EGFR-AS1. CO is currently classified in Weedon's Skin Pathology as an adnexal tumor, although the cell of origin is unknown.[1] It is unclear whether this neoplasm occurs due to a specific mutation, copy number alteration, or another pathogenesis.
- Subjects
NUCLEOTIDE sequencing; LINCRNA
- Publication
International Journal of Dermatology, 2023, Vol 62, Issue 4, pe244
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/ijd.16137