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- Title
Subcorneal pustular dermatosis successfully treated with low‐dose doxycycline.
- Authors
Borgia, Francesco; Campitiello, Alessio; Di Bartolomeo, Luca; Cardia, Roberta; Marafioti, Ilenia; Cannavò, Serafinella P.
- Abstract
Dear Editor, First described by Sneddon and Wilkinson in 1956, subcorneal pustular dermatosis (SPD) is a rare, chronic, relapsing disease included in the complex group of neutrophilic dermatoses.1,2 Typically affecting middle-aged women, it is characterized by a symmetrical sterile pustular eruption, which mainly involves the trunk, the intertriginous areas of the body, and the flexor aspects of the limbs. In conclusion, our case shows that low-dose doxycycline is an effective and safe therapy for SPD and may represent a useful alternative treatment modality with no relevant side effects. The treatment of choice is dapsone; corticosteroids, retinoids, phototherapy, infliximab, and pentoxyfilline have been used in resistant cases.3 Relapses after treatment discontinuation have been reported, and maintenance therapy should be considered.
- Subjects
TREATMENT effectiveness; DOXYCYCLINE; MYCOPLASMA pneumoniae infections; SJOGREN'S syndrome
- Publication
International Journal of Dermatology, 2021, Vol 60, Issue 9, pe375
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/ijd.15530