We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Pro-Inflammatory Diet Is Associated with Adiposity during Childhood and with Adipokines and Inflammatory Markers at 11 Years in Mexican Children.
- Authors
Barragán-Vázquez, Sofia; Ariza, Ana Carolina; Ramírez Silva, Ivonne; Pedraza, Lilia Susana; Rivera Dommarco, Juan A.; Ortiz-Panozo, Eduardo; Zambrano, Elena; Reyes Castro, Luis A.; Shivappa, Nitin; Hébert, James R.; Martorell, Reynaldo; Stein, Aryeh D.; Barraza-Villarreal, Albino; Romieu, Isabelle; Avila-Jiménez, Laura; Ramakrishnan, Usha
- Abstract
There is limited evidence about the inflammatory potential of diet in children. The aim of this study was to evaluate the association between the Children's Dietary Inflammatory Index (C-DII) from 5 to 11 years with adiposity and inflammatory biomarkers in Mexican children. We analyzed 726 children from a birth cohort study with complete dietary information and measurements to evaluate adiposity at 5, 7 and 11 y and 286 children with IL-6, hsCRP, leptin and adiponectin information at 11 y. C-DII trajectories were estimated using latent class linear mixed models. We used linear mixed models for adiposity and logistic and multinomial regression for biomarkers. In girls, each one-point increase in C-DII score was associated with greater adiposity (abdominal-circumference 0.41%, p = 0.03; skinfold-sum 1.76%, p = 0.01; and BMI Z-score 0.05, p = 0.01). At 11 y the C-DII was associated with greater leptin (34% ≥ 13.0 ng/mL, p = 0.03) and hsCRP concentrations (29% ≥ 3.00 mg/L, p = 0.06) and lower adiponectin/leptin ratio (75% < 2.45, p = 0.02). C-DII trajectory 3 in boys was associated with a 75.2% (p < 0.01) increase in leptin concentrations and a 37.9% decrease (p = 0.02) in the adiponectin/leptin ratio. This study suggests that the inflammatory potential of diet may influence adiposity in girls and the homeostasis of adipose tissue and chronic subclinical inflammation in 11-year-old children.
- Subjects
MEXICO; RISK of childhood obesity; INFLAMMATION; BIOMARKERS; C-reactive protein; DIET; HOMEOSTASIS; INTERLEUKINS; RISK assessment; SEX distribution; LEPTIN; LOGISTIC regression analysis; ADIPONECTIN; ADIPOKINES; WAIST circumference; STATISTICAL models; CHILDREN
- Publication
Nutrients, 2020, Vol 12, Issue 12, p3658
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu12123658