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- Title
Effect of Publicly Reported Aortic Valve Surgery Outcomes on Valve Surgery in Injection Drug– and Non–Injection Drug–Associated Endocarditis.
- Authors
Kimmel, Simeon D; Walley, Alexander Y; Linas, Benjamin P; Kalesan, Bindu; Awtry, Eric; Dobrilovic, Nikola; White, Laura; LaRochelle, Marc
- Abstract
Background Injection drug use–associated infective endocarditis (IDU-IE) is rising and valve surgery is frequently indicated. The effect of initiating public outcomes reporting for aortic valve surgery on rates of valve surgery and in-hospital mortality for endocarditis is not known. Methods For an interrupted time series analysis, we used data from the National Inpatient Sample, a representative sample of United States inpatient hospitalizations, from January 2010 to September 2015. We included individuals aged 18–65 with an International Classification of Diseases, Ninth Revision (ICD-9) diagnosis of endocarditis. We defined IDU-IE using a validated combination of ICD-9 codes. We used segmented logistic regression to assess for changes in valve replacement and in-hospital mortality rates after the public reporting initiation in January 2013. Results We identified 7322 hospitalizations for IDU-IE and 23 997 for non–IDU-IE in the sample, representing 36 452 national IDU-IE admissions and 119 316 non-IDU admissions, respectively. Following the implementation of public reporting in 2013, relative to baseline trends, the odds of valve replacement decreased by 4.0% per quarter (odds ratio [OR] 0.96, 95% confidence interval [CI] 0.93–0.99), with no difference by IDU status. The odds of an in-patient death decreased by 2.0% per quarter for both IDU-IE and non–IDU-IE cases following reporting (OR 0.98, 95% CI 0.97–0.99). Conclusions Initiating public reporting was associated with a significant decrease in valve surgery for all IE cases, regardless of IDU status, and a reduction in-hospital mortality for patients with IE. Patients with IE may have less access to surgery as a consequence of public reporting. To understand how reduced valve surgery impacts overall mortality, future studies should examine the postdischarge mortality rate.
- Subjects
AORTIC valve surgery; INTRAVENOUS drug abuse; COMPARATIVE studies; CONFIDENCE intervals; INFECTIVE endocarditis; NOSOLOGY; TIME series analysis; LOGISTIC regression analysis; DISCLOSURE; TREATMENT effectiveness; ODDS ratio; DISEASE complications
- Publication
Clinical Infectious Diseases, 2020, Vol 71, Issue 3, p480
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz834