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- Title
Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented With Acute Myeloid Leukemia After Smallpox Vaccination.
- Authors
Lindholm, David A; Fisher, Raymond D; Montgomery, Jay R; Davidson, Whitni; Yu, Patricia A; Yu, Yon C; Burgado, Jillybeth; Wilkins, Kimberly; Petersen, Brett W; Okulicz, Jason F
- Abstract
Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.
- Subjects
ANTIVIRAL agents; DRUG side effects; COMBINED modality therapy; IMMUNOSUPPRESSION; POXVIRUS diseases; PREVENTIVE health services; SMALLPOX vaccines; MILITARY personnel; ACUTE myeloid leukemia; DISEASE risk factors
- Publication
Clinical Infectious Diseases, 2019, Vol 69, Issue 12, p2205
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz286