We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Prevalence and genotypes of human parechovirus in stool samples from hospitalized children in Shanghai, China, 2008 and 2009.
- Authors
Zhong, Huaqing; Lin, Yong; Sun, Jiae; Su, Liyun; Cao, Lingfeng; Yang, Yi; Xu, Jin
- Abstract
Human parechoviruses (HPeVs) are widespread pathogens belonging to the Picornavirus family. The aim of the present study was to assess the prevalence and genetic diversity of HPeV in Shanghai, China, during a HPeV screening program in 2008 and 2009. Of 300 stool samples from children under the age of 5 years with acute diarrhea seen at Children's Hospital, Fudan University, Shanghai, China, 165 (55%) were HPeV-positive. The median age of infected children was 3 months. The prevalence of HPeV was high (57%) in infants up to 2 years old but dropped to 30.4% in children between 2 and 5 years old. The prevalence did not differ by sex. Infections were present throughout the year but peaked in July and August. The most predominant genotype was HPeV1. Of the 139 strains, 4 were found in 9 samples: HPeV4 (n = 4), HPeV5 (n = 1), HPeV6 (n = 1), and HPeV8 (n = 3). This study provided useful data on the epidemiology of HPeV infection by documenting the distribution of genotypes, age of infection, and seasonal patterns in Shanghai, China. J. Med. Virol. 83:1428-1434, 2011. © 2011 Wiley-Liss, Inc.
- Publication
Journal of Medical Virology, 2011, Vol 83, Issue 8, p1428
- ISSN
0146-6615
- Publication type
Article
- DOI
10.1002/jmv.22114