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- Title
Adoption of Pharmacogenomic Testing by US Physicians: Results of a Nationwide Survey.
- Authors
Stanek, E J; Sanders, C L; Taber, K A Johansen; Khalid, M; Patel, A; Verbrugge, R R; Agatep, B C; Aubert, R E; Epstein, R S; Frueh, F W
- Abstract
To develop a benchmark measure of US physicians' level of knowledge and extent of use of pharmacogenomic testing, we conducted an anonymous, cross-sectional, fax-based, national survey. Of 397,832 physicians receiving the survey questionnaire, 10,303 (3%) completed and returned it; the respondents were representative of the overall US physician population. The factors associated with the decision to test were evaluated using χ2 and multivariate logistic regression. Overall, 97.6% of responding physicians agreed that genetic variations may influence drug response, but only 10.3% felt adequately informed about pharmacogenomic testing. Only 12.9% of physicians had ordered a test in the previous 6 months, and 26.4% anticipated ordering a test in the next 6 months. Early and future adopters of testing were more likely to have received training in pharmacogenomics, but only 29.0% of physicians overall had received any education in the field. Our findings highlight the need for more effective physician education on the clinical value, availability, and interpretation of pharmacogenomic tests.
- Subjects
UNITED States; PHARMACOGENOMICS; EDUCATION of physicians; LOGISTIC regression analysis; PHARMACODYNAMICS
- Publication
Clinical Pharmacology & Therapeutics, 2012, Vol 91, Issue 3, p450
- ISSN
0009-9236
- Publication type
Article
- DOI
10.1038/clpt.2011.306