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- Title
A Green Light for Stop Mutations.
- Authors
Cohen-Cymberknoh, Malena; Slae, Mordechai; Wilschanski, Michael
- Abstract
The article discusses the study "Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations" by V. Mutyam, J. Sharma, Y. Li and colleagues, that was published within the issue. Topics covered include combined use of Galapagos/AbbVie cystic fibrosis transmembrane conductance regulator (CFTR) correctors and potentiators, heterologous Fischer rat thyroid cells, and genetically engineered human bronchial epithelial cells.
- Subjects
CYSTIC fibrosis transmembrane conductance regulator; NONSENSE mutation; CYSTIC fibrosis; EPITHELIAL cells; DRUG efficacy
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2021, Vol 64, Issue 5, p531
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2021-0060ED