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- Title
Extrapelvic Metastases in Endometrial Stromal Sarcomas: A Clinicopathological Review With Immunohistochemical and Molecular Characterization.
- Authors
Baniak, Nick; Adams, Scott; Lee, Cheng-Han; Chibbar, Rajni; Kanthan, Rani
- Abstract
Endometrial stromal sarcoma is a rare uterine tumor associated with favorable outcomes despite its ability to recur and metastasize to distant sites. Most recurrences are local, being limited to the abdomen/pelvis, but distant metastases can occur. Metastatic endometrial stromal sarcoma can occur many months to years after the original diagnosis or may present prior to the primary, potentially creating a diagnostic challenge. We report a bi-institutional review of 10 cases of endometrial stromal sarcoma with extrapelvic metastases without a prior history of endometriosis. The histologic, immunophenotypic, and molecular characteristics of these tumors are analyzed in the context of a relevant literature review.
- Subjects
DIAGNOSIS of endometrial cancer; METASTASIS; SARCOMA; PELVIC tumors; ABDOMINAL tumors; ENDOMETRIOSIS; UTERINE tumors
- Publication
International Journal of Surgical Pathology, 2019, Vol 27, Issue 2, p208
- ISSN
1066-8969
- Publication type
Case Study
- DOI
10.1177/1066896918794278