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- Title
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features.
- Authors
Zhen Wang; Qing-Tao Kong; Xin-Hu Wu; Xi-Xu Zhu; Wang, Zhen; Kong, Qing-Tao; Wu, Xin-Hu; Zhu, Xi-Xu
- Abstract
Gliosarcoma is a rare primary malignant tumor of the central nervous system with poor prognosis. The median survival time of this disease ranges from 6 months to 14.8 months. However, a computer literature search indicated few long-term survivors. We investigated a case of a survivor of gliosarcoma with radiation-induced meningeal sarcomas, who showed no indication of recurrence for more than 9 years. A battery of molecular studies was performed to develop a molecular profile of this unique patient. We also reviewed the distinct clinical and molecular features of the tumor.
- Subjects
MENINGEAL cancer; SURVIVAL analysis (Biometry); CANCER radiotherapy; GLIOMAS; CANCER relapse; PATIENTS; PROGNOSIS; DNA; ENZYMES; GENES; MAGNETIC resonance imaging; OXIDOREDUCTASES; PHOSPHATASES; PROTEINS; RADIATION carcinogenesis; MENINGES; TREATMENT effectiveness; TUMORS
- Publication
Journal of Cancer Research & Therapeutics, 2015, Vol 11, Issue 3, p651
- ISSN
0973-1482
- Publication type
case study
- DOI
10.4103/0973-1482.137995