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- Title
THE DIABETES-TUBERCULOSIS CO-EPIDEMIC: THE INTERACTION BETWEEN INDIVIDUAL AND SOCIO-ECONOMIC RISK FACTORS.
- Authors
Firănescu, Adela-Gabriela; Popa, Adina; Roşu, Maria-Magdalena; Protasiewicz, Diana Cristina; Popa, Simona Georgiana; Ioana, Mihai; Moța, Maria
- Abstract
Worldwide, tuberculosis (TB) is a major cause of morbi-mortality, about 30% of the population having a Mycobacterium tuberculosis infection. Patients with diabetes mellitus (DM) have a threefold increased risk of developing the disease. The prevalence of DM is rapidly increasing, especially in countries with low and middle income, where TB incidence is also increased, thus baffling the efforts for TB control. The DM-TB coepidemic is more frequent in married, older men, with reduced level of education, low income, without a steady job, with lifestyle habits such as alcohol consumption, smoking, sedentarism, living in an urban environment, in crowded areas, in insanitary conditions. These patients have a higher body mass index (BMI) compared with those without DM and frequently present family history of TB, family history of DM, longer duration of DM and reduced glycemic control. TB associated with DM is usually asymptomatic, more contagious, multidrug resistant and is significantly associated with an increased risk of therapy failure, relapse and even death. Thus, the DM-TB comorbidity represents a threat to public health and requires the implementation of urgent measures in order to both prevent and manage the two diseases.
- Subjects
TUBERCULOSIS; MYCOBACTERIUM tuberculosis; PEOPLE with diabetes; BODY mass index; ALCOHOL drinking; GLYCEMIC control
- Publication
Romanian Journal of Diabetes Nutrition & Metabolic Diseases, 2017, Vol 24, Issue 1, p71
- ISSN
2068-8245
- Publication type
Article
- DOI
10.1515/rjdnmd-2017-0009