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- Title
Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin.
- Authors
Williams, Margaret M.; Sen, Kathryn A.; Weigand, Michael R.; Skoff, Tami H.; Cunningham, Victoria A.; Halse, Tanya A.; Tondella, M. Lucia; Sen, Kathryn; CDC Pertussis Working Group
- Abstract
A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin-deficient, pertactin wild-type showed that the strains carry the same 28-kb deletion in similar genomes.
- Subjects
BORDETELLA pertussis; PERTUSSIS toxin; VACCINATION of infants; DELETION mutation; GENOMES; WHOOPING cough; BACTERIAL toxins; MEMBRANE proteins; GENETIC mutation; WHOOPING cough vaccines; PREVENTION
- Publication
Emerging Infectious Diseases, 2016, Vol 22, Issue 2, p319
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2202.151332