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- Title
Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic.
- Authors
Nouvel, Laurent X.; Kassa-Kelembho, Eric; Dos Vultos, Tiago; Zandanga, Germain; Rauzier, Jean; Lafoz, Carmen; Martin, Carlos; Blazquez, Jesus; Talarmin, Antoine; Gicquel, Brigitte
- Abstract
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
- Subjects
BANGUI (Central African Republic); CENTRAL African Republic; MYCOBACTERIUM tuberculosis; MULTIDRUG resistance; NUCLEOTIDES; GENETIC polymorphisms
- Publication
Emerging Infectious Diseases, 2006, Vol 12, Issue 9, p1454
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid1209.060361