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- Title
Venezuelan equine encephalitis virus, southern Mexico.
- Authors
Estrada-Franco, José G.; Navarro-Lopez, Roberto; Freier, Jerome E.; Cordova, Dionicio; Clements, Tamara; Moncayo, Abelardo; Kang, Wenli; Gomez-Hernandez, Carlos; Rodriguez-Dominguez, Gabriela; Ludwig, George V.; Weaver, Scott C.; Estrada-Franco, José G
- Abstract
Equine epizootics of Venezuelan equine encephalitis (VEE) occurred in the southern Mexican states of Chiapas in 1993 and Oaxaca in 1996. To assess the impact of continuing circulation of VEE virus (VEEV) on human and animal populations, serologic and viral isolation studies were conducted in 2000 to 2001 in Chiapas State. Human serosurveys and risk analyses indicated that long-term endemic transmission of VEEV occurred among villages with seroprevalence levels of 18% to 75% and that medical personnel had a high risk for VEEV exposure. Seroprevalence in wild animals suggested cotton rats as possible reservoir hosts in the region. Virus isolations from sentinel animals and genetic characterizations of these strains indicated continuing circulation of a subtype IE genotype, which was isolated from equines during the recent VEE outbreaks. These data indicate long-term enzootic and endemic VEEV circulation in the region and continued risk for disease in equines and humans.
- Subjects
CHIAPAS (Mexico); MEXICO; EQUINE encephalomyelitis; EPIDEMIC encephalitis; HORSE viral diseases; ZOONOSES; ANIMAL experimentation; ANIMAL populations; ANIMAL diseases; COMPARATIVE studies; EPIDEMIOLOGICAL research; BIOLOGICAL evolution; GENOMES; HORSES; RESEARCH methodology; MEDICAL cooperation; RESEARCH; RESEARCH funding; RNA; RNA viruses; SENTINEL health events; EVALUATION research
- Publication
Emerging Infectious Diseases, 2004, Vol 10, Issue 12, p2113
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid1012.040393