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- Title
Copper-Catalyzed C-2 Arylation or Vinylation of Indole Derivatives with Iodonium Salts.
- Authors
Liu, Chuan; Zhang, Wei; Dai, Li ‐ Xin; You, Shu ‐ Li
- Abstract
Copper-catalyzed C-2 arylation and vinylation of indole derivatives with iodonium salts have been realized. This method, featuring a simple operational procedure, mild reaction conditions, and a wide substrate scope, provided versatile indole derivatives with direct and selective functionalization at the C-2 position of the indole core. In the presence of excess amounts of iodonium salts, cascade C-2 arylation and dearomatization through the C-3 arylation reaction also proceeded smoothly.
- Subjects
COPPER; INDOLE derivatives; NATIVE element minerals; TRANSITION metals; CATALYSIS
- Publication
Chemistry - An Asian Journal, 2014, Vol 9, Issue 8, p2113
- ISSN
1861-4728
- Publication type
Article
- DOI
10.1002/asia.201402071