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- Title
OMPHALOCELE: ANATOMIC AND CLINICAL CONSIDERATIONS.
- Authors
Ţarcă, Elena; Trandafir, Laura Mihaela; Luca, Alina; Roşu, Solange Tamara; Popescu, Mihaela Roxana; Temneanu, Oana-Raluca
- Abstract
Despite the scientific development of medicine, medical technologies and important advances in antenatal diagnosis and postnatal treatment, congenital malformations are a major cause of neonatal morbidity and mortality in numerous countries around the world. The omphalocele is the most common congenital defect of the anterior abdominal wall; sometimes it can occur isolated, but in most cases is associated with other malformations or chromosomal anomalies. There is a progress in the field of embryology and pathophysiology, but thus the molecular mechanisms of occurrence of the anterior abdominal wall, the physiological umbilical hernia during embryonic life and appearance of omphalocele are incompletely understood. The prenatal and postnatal prognosis of omphalocele is greatly influenced by the volume of abdominal herniated organs and by the association of other congenital malformations, which adds its own morbidity and mortality to the treatment difficulties of the underlying condition.
- Subjects
UMBILICAL hernia; CLOACAL exstrophy
- Publication
Romanian Journal of Functional & Clinical, Macro & Microscopical Anatomy & of Anthropology / Revista Româna de Anatomie Functionala si Clinica, Macro si Microscopica si de Antropologie, 2018, Vol 17, Issue 3, p226
- ISSN
1583-4026
- Publication type
Country Report