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- Title
Primary Pleural Angiosarcoma Treated with Nivolumab and Ipilimumab: A Case Report.
- Authors
Nakamura, Mikako; Watanabe, Kaoru; Nishimura, Taku; Yoshida, Keishi; Fukumoto, Kento; Hiyama, Noriko; Masuda, Yoshio; Morikawa, Teppei; Matsumoto, Jun; Usui, Kazuhiro
- Abstract
Primary pleural angiosarcoma (PPA) is a rare and clinically fatal pleural tumor originating from vascular endothelial cells. Herein, we presented the case of a 73-year-old man who was referred to our emergency room with complaints of right chest and back pain for a few days. Chest computed tomography revealed massive pleural effusion and a large mass in the right chest cavity. Thoracoscopic examination demonstrated a large hemorrhagic tumor on the parietal pleura whose pathological analysis indicated PPA. The patient received immunotherapy combined with nivolumab and ipilimumab. A cycle of nivolumab and ipilimumab improved his hemorrhagic anemia and reduced the pleural effusion and tumor size. This treatment outcome suggests that nivolumab and ipilimumab comprise a vital treatment option for PPA.
- Subjects
ANGIOSARCOMA; NIVOLUMAB; IPILIMUMAB; VASCULAR endothelial cells; CHEST (Anatomy); TREATMENT effectiveness
- Publication
Case Reports in Oncology, 2023, Vol 16, Issue 1, p81
- ISSN
1662-6575
- Publication type
Article
- DOI
10.1159/000529447