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- Title
CD5+ Immunophenotype in the Bone Marrow but Not in the Peripheral Blood in a Patient with Hairy Cell Leukemia.
- Authors
Usha, Lydia; Bradlow, Basil; Stock, Wendy; Platanias, Leonidas C.
- Abstract
We report the case of a patient with rare CD5+ hairy cell leukemia, which was unusual, as there was also a discrepancy between the bone marrow and peripheral blood immunophenotypes. We propose that some degree of maturation within the malignant clone and the predominance of more mature CD5– hairy cells in the peripheral blood can explain this observation. The patient was treated with a conventional course of cladribine (2′-chlorodeoxyadenosine) and achieved complete remission. We conclude that the unusual CD5+ immunophenotype of this patient did not affect prognosis or change the response to standard therapy.Copyright © 2000 S. Karger AG, Basel
- Subjects
IMMUNOPHENOTYPING; HAIRY cell leukemia; BONE marrow diseases; BONE marrow; BLOOD; LYMPHOCYTE classification; SPONTANEOUS cancer regression
- Publication
Acta Haematologica, 2000, Vol 103, Issue 4, p210
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000041052