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- Title
Reply: The spectrum of complement pathway activation is integral to the pathogenesis of severe COVID-19.
- Authors
Lee, Myoung-Hwa; Perl, Daniel P; Steiner, Joseph; Pasternack, Nicholas; Li, Wenxue; Maric, Dragan; Safavi, Farinaz; Horkayne-Szakaly, Iren; Jones, Robert; Stram, Michelle N; Moncur, Joel T; Hefti, Marco; Folkerth, Rebecca D; Nath, Avindra
- Abstract
REFERENCES 1 Magro C, Nuovo G. The spectrum of complement pathway activation is integral to the pathogenesis of severe COVID-19. As they point out, there might be additional mechanisms of vascular injury that may include direct injury by the spike protein of SARS-CoV-2 and complement activation via the mannan binding lectin pathway.
- Subjects
COMPLEMENT activation; COVID-19; CELL adhesion molecules; PATHOGENESIS; BLOOD proteins
- Publication
Brain: A Journal of Neurology, 2022, Vol 145, Issue 11, pe118
- ISSN
0006-8950
- Publication type
journal article
- DOI
10.1093/brain/awac353