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- Title
Spatial and episodic memory tasks promote temporal lobe interictal spikes.
- Authors
Vivekananda, Umesh; Bush, Daniel; Bisby, James A.; Diehl, Beate; Jha, Ashwani; Nachev, Parashkev; Rodionov, Roman; Burgess, Neil; Walker, Matthew C.
- Abstract
Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to specifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within these regions, whereas a nonhippocampal dependent task did not. This indicates that interictal spike frequency may reflect the processing demands being placed on specific functional-anatomical networks in epilepsy. ANN NEUROL 2019;86:304-309.
- Subjects
TEMPORAL lobe; SPATIAL memory; EPISODIC memory; EPILEPSY &; psychology; TASKS; NEOCORTEX
- Publication
Annals of Neurology, 2019, Vol 86, Issue 2, p304
- ISSN
0364-5134
- Publication type
journal article
- DOI
10.1002/ana.25519