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- Title
The Synthesis of 3-Amino-pyrazine-2-carbohydrazide and 3-Amino- N′-methylpyrazine-2-carbohydrazide Derivatives.
- Authors
Milczarska, Barbara; Gobis, Katarzyna; Foks, Henryk; Golunski, Lukasz; Sowinski, Pawel
- Abstract
In research of new biologically active compounds, the reactions of amino-pyrazin-2-hydrazide and methylhydrazide with isothiocyanates, aromatic aldehydes, ketones, CS2, and formic acid were made. New thiosemicarbazides, 1,3,4-thiadiazoles, 1,3,4-oxadiazoles, and 1,2,4-triazoles were obtained. New 4-oxopteridine derivative 26 was also synthesized.
- Subjects
ORGANIC synthesis; HYDRAZIDES; PYRAZINES; BIOACTIVE compounds; AROMATIC aldehydes; KETONES; ISOTHIOCYANATES; THIADIAZOLES; CHEMICAL derivatives
- Publication
Journal of Heterocyclic Chemistry, 2012, Vol 49, Issue 4, p845
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.877