We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Transitions among five polymorphs of chlorpropamide near the melting point.
- Authors
Drebushchak, V.; Drebushchak, Tatiana; Chukanov, N.; Boldyreva, Elena
- Abstract
Five polymorphs of chlorpropamide (α, β, δ, γ, and ε) were investigated near the melting point by using DSC. Structure of samples was tested by X-ray powder diffraction. Four first polymorphs were found to transform into ε-polymorph, which melts at T m=128°C, Δm H=24 kJ mol−1. Enthalpy of the polymorph transitions ranges from +3 kJ mol−1 for α→ε to −0.8 kJ mol−1 for β→ε. Structure of three first polymorphs was published elsewhere, and the structure of δ-polymorph is published for the first time. XRPD patterns for all polymorphs are reported, together with the atomic coordinates for the δ-polymorph.
- Subjects
POLYMORPHISM (Zoology); CHLORPROPAMIDE; MELTING points; CALORIMETRY; ENTHALPY
- Publication
Journal of Thermal Analysis & Calorimetry, 2008, Vol 93, Issue 2, p343
- ISSN
1388-6150
- Publication type
Article
- DOI
10.1007/s10973-007-8822-0