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Bridging structural biology and clinical research through in-tissue cryo-electron tomography.
Published in:
EMBO Journal, 2024, v. 43, n. 21, p. 4810, doi. 10.1038/s44318-024-00216-z
By:
- Kixmoeller, Kathryn;
- Creekmore, Benjamin C;
- Lee, Edward B;
- Chang, Yi-Wei
Publication type:
Article
Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01353-4
By:
- Ameen-Ali, Kamar E.;
- Bretzin, Abigail;
- Lee, Edward B.;
- Folkerth, Rebecca;
- Hazrati, Lili-Naz;
- Iacono, Diego;
- Keene, C. Dirk;
- Kofler, Julia;
- Kovacs, Gabor G.;
- Nolan, Amber;
- Perl, Daniel P.;
- Priemer, David S.;
- Smith, Douglas H.;
- Wiebe, Douglas J.;
- Stewart, William;
- CONNECT-TBI Investigators;
- Al-Sarraj, Safa;
- Cortes, Etty;
- Crary, John;
- Dams-O'Connor, Kristin
Publication type:
Article
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01334-7
By:
- Feng, Tuancheng;
- Luan, Lin;
- Katz, Isabel Iscol;
- Ullah, Mohammed;
- Van Deerlin, Vivianna M.;
- Trojanowski, John Q.;
- Lee, Edward B.;
- Hu, Fenghua
Publication type:
Article
Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01290-8
By:
- Kim, Benjamin J.;
- Lee, Vivian;
- Lee, Edward B.;
- Saludades, Adrienne;
- Trojanowski, John Q.;
- Dunaief, Joshua L.;
- Grossman, Murray;
- Irwin, David J.
Publication type:
Article
Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01275-7
By:
- Ravikumar, Sadhana;
- Wisse, Laura E. M.;
- Lim, Sydney;
- Ittyerah, Ranjit;
- Xie, Long;
- Bedard, Madigan L.;
- Das, Sandhitsu R.;
- Lee, Edward B.;
- Tisdall, M. Dylan;
- Prabhakaran, Karthik;
- Lane, Jacqueline;
- Detre, John A.;
- Mizsei, Gabor;
- Trojanowski, John Q.;
- Robinson, John L.;
- Schuck, Theresa;
- Grossman, Murray;
- Artacho-Pérula, Emilio;
- de Onzoño Martin, Maria Mercedes Iñiguez;
- del Mar Arroyo Jiménez, María
Publication type:
Article
Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01233-3
By:
- Iida, Megan A.;
- Farrell, Kurt;
- Walker, Jamie M.;
- Richardson, Timothy E.;
- Marx, Gabriel A.;
- Bryce, Clare H.;
- Purohit, Dushyant;
- Ayalon, Gai;
- Beach, Thomas G.;
- Bigio, Eileen H.;
- Cortes, Etty P.;
- Gearing, Marla;
- Haroutunian, Vahram;
- McMillan, Corey T.;
- Lee, Edward B.;
- Dickson, Dennis W.;
- McKee, Ann C.;
- Stein, Thor D.;
- Trojanowski, John Q.;
- Woltjer, Randall L.
Publication type:
Article
COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI).
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01122-9
By:
- Smith, Douglas H.;
- Dollé, Jean-Pierre;
- Ameen-Ali, Kamar E.;
- Bretzin, Abigail;
- Cortes, Etty;
- Crary, John F.;
- Dams-O'Connor, Kristen;
- Diaz-Arrastia, Ramon;
- Edlow, Brian L.;
- Folkerth, Rebecca;
- Hazrati, Lili-Naz;
- Hinds, Sidney R.;
- Iacono, Diego;
- Johnson, Victoria E.;
- Keene, C. Dirk;
- Kofler, Julia;
- Kovacs, Gabor G.;
- Lee, Edward B.;
- Manley, Geoffrey;
- Meaney, David
Publication type:
Article
Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01233-3
By:
- Iida, Megan A.;
- Farrell, Kurt;
- Walker, Jamie M.;
- Richardson, Timothy E.;
- Marx, Gabriel A.;
- Bryce, Clare H.;
- Purohit, Dushyant;
- Ayalon, Gai;
- Beach, Thomas G.;
- Bigio, Eileen H.;
- Cortes, Etty P.;
- Gearing, Marla;
- Haroutunian, Vahram;
- McMillan, Corey T.;
- Lee, Edward B.;
- Dickson, Dennis W.;
- McKee, Ann C.;
- Stein, Thor D.;
- Trojanowski, John Q.;
- Woltjer, Randall L.
Publication type:
Article
Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01129-2
By:
- Giannini, Lucia A. A.;
- Peterson, Claire;
- Ohm, Daniel;
- Xie, Sharon X.;
- McMillan, Corey T.;
- Raskovsky, Katya;
- Massimo, Lauren;
- Suh, EunRah;
- Van Deerlin, Vivianna M.;
- Wolk, David A.;
- Trojanowski, John Q.;
- Lee, Edward B.;
- Grossman, Murray;
- Irwin, David J.
Publication type:
Article
Pathogenesis of Scleroderma Current Concepts.
Published in:
International Journal of Dermatology, 1984, v. 23, n. 2, p. 85, doi. 10.1111/j.1365-4362.1984.tb05678.x
By:
- Lee, Edward B.;
- Anhalt, Grant J.;
- Voorhees, John J.;
- Diaz, Luis A.
Publication type:
Article
Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.
Published in:
Frontiers in Human Neuroscience, 2017, v. 10, p. 1, doi. 10.3389/fnhum.2016.00693
By:
- Spotorno, Nicola;
- McMillan, Corey T.;
- Irwin, David J.;
- Clark, Robin;
- Lee, Edward B.;
- Trojanowski, John Q.;
- Weintraub, Daniel;
- Grossman, Murray;
- Bischof, Gerard Nisal;
- Beason-Held, Lori
Publication type:
Article
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 7, p. 2975, doi. 10.1093/brain/awad145
By:
- Young, Alexandra L;
- Vogel, Jacob W;
- Robinson, John L;
- McMillan, Corey T;
- Ossenkoppele, Rik;
- Wolk, David A;
- Irwin, David J;
- Elman, Lauren;
- Grossman, Murray;
- Lee, Virginia M Y;
- Lee, Edward B;
- Hansson, Oskar
Publication type:
Article
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 7, p. 2897, doi. 10.1093/brain/awac479
By:
- Ortiz, Ashley P Viera;
- Cajka, Gregory;
- Olatunji, Olamide A;
- Mikytuck, Bailey;
- Shalem, Ophir;
- Lee, Edward B
Publication type:
Article
Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 6, p. 2557, doi. 10.1093/brain/awad059
By:
- Robinson, John L;
- Xie, Sharon X;
- Baer, Daniel R;
- Suh, EunRan;
- Deerlin, Vivianna M Van;
- Loh, Nicholas J;
- Irwin, David J;
- McMillan, Corey T;
- Wolk, David A;
- Chen-Plotkin, Alice;
- Weintraub, Daniel;
- Schuck, Theresa;
- Lee, Virginia M Y;
- Trojanowski, John Q;
- Lee, Edward B
Publication type:
Article
Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease.
Published in:
2022
By:
- Steinkellner, Thomas;
- Conrad, William S;
- Kovacs, Imre;
- Rissman, Robert A;
- Lee, Edward B;
- Trojanowski, John Q;
- Freyberg, Zachary;
- Roy, Subhojit;
- Luk, Kelvin C;
- Lee, Virginia M;
- Hnasko, Thomas S
Publication type:
journal article
The development and convergence of co-pathologies in Alzheimer's disease.
Published in:
2021
By:
- Robinson, John L;
- Richardson, Hayley;
- Xie, Sharon X;
- Suh, EunRan;
- Deerlin, Vivianna M Van;
- Alfaro, Brian;
- Loh, Nicholas;
- Porras-Paniagua, Matias;
- Nirschl, Jeffrey J;
- Wolk, David;
- Lee, Virginia M -Y;
- Lee, Edward B;
- Trojanowski, John Q;
- Van Deerlin, Vivianna M
Publication type:
journal article
Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration.
Published in:
2020
By:
- Robinson, John L;
- Porta, Sílvia;
- Garrett, Filip G;
- Zhang, Panpan;
- Xie, Sharon X;
- Suh, EunRan;
- Deerlin, Vivianna M Van;
- Abner, Erin L;
- Jicha, Gregory A;
- Barber, Justin M;
- Lee, Virginia M -Y;
- Lee, Edward B;
- Trojanowski, John Q;
- Nelson, Peter T;
- Van Deerlin, Vivianna M
Publication type:
journal article
ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration.
Published in:
2020
By:
- Cousins, Katheryn A Q;
- Irwin, David J;
- Wolk, David A;
- Lee, Edward B;
- Shaw, Leslie M J;
- Trojanowski, John Q;
- Re, Fulvio Da;
- Gibbons, Garrett S;
- Grossman, Murray;
- Phillips, Jeffrey S;
- Da Re, Fulvio
Publication type:
journal article
Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease.
Published in:
2020
By:
- Arena, John D;
- Smith, Douglas H;
- Lee, Edward B;
- Gibbons, Garrett S;
- Irwin, David J;
- Robinson, John L;
- Lee, Virginia M -Y;
- Trojanowski, John Q;
- Stewart, William;
- Johnson, Victoria E
Publication type:
journal article
Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer's disease.
Published in:
2019
By:
- Phillips, Jeffrey S;
- Re, Fulvio Da;
- Irwin, David J;
- McMillan, Corey T;
- Vaishnavi, Sanjeev N;
- Xie, Sharon X;
- Lee, Edward B;
- Cook, Philip A;
- Gee, James C;
- Shaw, Leslie M;
- Trojanowski, John Q;
- Wolk, David A;
- Grossman, Murray;
- Da Re, Fulvio
Publication type:
journal article
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated.
Published in:
2018
By:
- Robinson, John L.;
- Lee, Edward B.;
- Xie, Sharon X.;
- Rennert, Lior;
- Suh, EunRan;
- Bredenberg, Colin;
- Caswell, Carrie;
- Van Deerlin, Vivianna M.;
- Ning Yan;
- Yousef, Ahmed;
- Hurtig, Howard I.;
- Siderowf, Andrew;
- Grossman, Murray;
- McMillan, Corey T.;
- Miller, Bruce;
- Duda, John E.;
- Irwin, David J.;
- Wolk, David;
- Elman, Lauren;
- McCluskey, Leo
Publication type:
journal article
Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia.
Published in:
2018
By:
- Irwin, David J.;
- McMillan, Corey T.;
- Xie, Sharon X.;
- Rascovsky, Katya;
- Van Deerlin, Vivianna M.;
- Coslett, H. Branch;
- Hamilton, Roy;
- Aguirre, Geoffrey K.;
- Lee, Edward B.;
- Lee, Virginia M. Y.;
- Trojanowski, John Q.;
- Grossman, Murray;
- Aguirre, Geoffrey
Publication type:
journal article
Polypathologic Associations with Gray Matter Atrophy in Neurodegenerative Disease.
Published in:
Journal of Neuroscience, 2024, v. 44, n. 6, p. 1, doi. 10.1523/JNEUROSCI.0808-23.2023
By:
- Phillips, Jeffrey S.;
- Robinson, John L.;
- Cousins, Katheryn A. Q.;
- Wolk, David A.;
- Lee, Edward B.;
- McMillan, Corey T.;
- Trojanowski, John Q.;
- Grossman, Murray;
- Irwin, David J.
Publication type:
Article
The ADNI4 Digital Study: A novel approach to recruitment, screening, and assessment of participants for AD clinical research.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 10, p. 7232, doi. 10.1002/alz.14234
By:
- Miller, Melanie J.;
- Diaz, Adam;
- Conti, Catherine;
- Albala, Bruce;
- Flenniken, Derek;
- Fockler, Juliet;
- Kwang, Winnie;
- Sacrey, Diana Truran;
- Ashford, Miriam T.;
- Skirrow, Caroline;
- Weston, Jack;
- Fristed, Emil;
- Farias, Sarah Tomaszewski;
- Korecka, Magda;
- Wan, Yang;
- Aisen, Paul S.;
- Beckett, Laurel;
- Harvey, Danielle;
- Lee, Edward B.;
- Petersen, Ronald C.
Publication type:
Article
A cross‐sectional study of α‐synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5114, doi. 10.1002/alz.13858
By:
- Tosun, Duygu;
- Hausle, Zachary;
- Iwaki, Hirotaka;
- Thropp, Pamela;
- Lamoureux, Jennifer;
- Lee, Edward B.;
- MacLeod, Karen;
- McEvoy, Sean;
- Nalls, Michael;
- Perrin, Richard J.;
- Saykin, Andrew J.;
- Shaw, Leslie M.;
- Singleton, Andrew B.;
- Lebovitz, Russ;
- Weiner, Michael W.;
- Blauwendraat, Cornelis
Publication type:
Article
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4043, doi. 10.1002/alz.13821
By:
- Wojtas, Aleksandra M.;
- Dammer, Eric B.;
- Guo, Qi;
- Ping, Lingyan;
- Shantaraman, Ananth;
- Duong, Duc M.;
- Yin, Luming;
- Fox, Edward J.;
- Seifar, Fatemeh;
- Lee, Edward B.;
- Johnson, Erik C. B.;
- Lah, James J.;
- Levey, Allan I.;
- Levites, Yona;
- Rangaraju, Srikant;
- Golde, Todd E.;
- Seyfried, Nicholas T.
Publication type:
Article
Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 3889, doi. 10.1002/alz.13777
By:
- Cousins, Katheryn A. Q.;
- Phillips, Jeffrey S.;
- Das, Sandhitsu R.;
- O'Brien, Kyra;
- Tropea, Thomas F.;
- Chen‐Plotkin, Alice;
- Shaw, Leslie M.;
- Nasrallah, Ilya M.;
- Mechanic‐Hamilton, Dawn;
- McMillan, Corey T.;
- Irwin, David J.;
- Lee, Edward B.;
- Wolk, David A.
Publication type:
Article
Neighborhood disadvantage reduces cognitive reserve independent of neuropathologic change.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2707, doi. 10.1002/alz.13736
By:
- Kim, Boram;
- Yannatos, Isabel;
- Blam, Kaitlin;
- Wiebe, Douglas;
- Xie, Sharon X.;
- McMillan, Corey T.;
- Mechanic‐Hamilton, Dawn;
- Wolk, David A.;
- Lee, Edward B.
Publication type:
Article
Tau‐neurodegeneration mismatch reveals vulnerability and resilience to comorbidities in Alzheimer's continuum.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1586, doi. 10.1002/alz.13559
By:
- Lyu, Xueying;
- Duong, Michael Tran;
- Xie, Long;
- de Flores, Robin;
- Richardson, Hayley;
- Hwang, Gyujoon;
- Wisse, Laura E. M.;
- DiCalogero, Michael;
- McMillan, Corey T.;
- Robinson, John L.;
- Xie, Sharon X.;
- Lee, Edward B.;
- Irwin, David J.;
- Dickerson, Bradford C.;
- Davatzikos, Christos;
- Nasrallah, Ilya M.;
- Yushkevich, Paul A.;
- Wolk, David A.;
- Das, Sandhitsu R.
Publication type:
Article
ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 5, p. 822, doi. 10.1002/alz.12233
By:
- Cousins, Katheryn A.Q.;
- Phillips, Jeffrey S.;
- Irwin, David J.;
- Lee, Edward B.;
- Wolk, David A.;
- Shaw, Leslie M.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Burke, Sarah E.;
- Kinney, Nikolas G.;
- Gibbons, Garrett S.;
- McMillan, Corey T.;
- Trojanowski, John Q.;
- Grossman, Murray
Publication type:
Article
P4‐707: A HYPOMORPH MUTATION OF THE TAU DISAGGREGASE VCP IS ASSOCIATED WITH VACUOLAR TAUOPATHY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1603, doi. 10.1016/j.jalz.2019.09.071
By:
- Darwich, Nabil F.;
- Phan, Jessica M.;
- Suh, EunRan R.;
- Toro, Camilo;
- Grossman, Murray;
- Irwin, David;
- McMillan, Corey T.;
- Aguirre, Geoff K.;
- Van Deerlin, Vivianna M.;
- Lee, Edward B.
Publication type:
Article
Cerebrospinal fluid α‐synuclein contributes to the differential diagnosis of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 8, p. 1052, doi. 10.1016/j.jalz.2018.02.015
By:
- Shi, Min;
- Tang, Lu;
- Toledo, Jon B.;
- Ginghina, Carmen;
- Wang, Hua;
- Aro, Patrick;
- Jensen, Poul H.;
- Weintraub, Daniel;
- Chen‐Plotkin, Alice S.;
- Irwin, David J.;
- Grossman, Murray;
- McCluskey, Leo;
- Elman, Lauren B.;
- Wolk, David A.;
- Lee, Edward B.;
- Shaw, Leslie M.;
- Trojanowski, John Q.;
- Zhang, Jing
Publication type:
Article
Cognitive decline associated with pathological burden in primary age-related tauopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, n. 9, p. 1048, doi. 10.1016/j.jalz.2017.01.028
By:
- Jefferson-George, Kyra S.;
- Wolk, David A.;
- Lee, Edward B.;
- McMillan, Corey T.
Publication type:
Article
Alteration of hypothalamic cellular dynamics in obesity.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 22, doi. 10.1172/JCI61562
By:
- Lee, Edward B.;
- Ahima, Rexford S.
Publication type:
Article
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 2, p. 726, doi. 10.1172/JCI44867
By:
- Igaz, Lionel M.;
- Kwong, Linda K.;
- Lee, Edward B.;
- Chen-Plotkin, Alice;
- Swanson, Eric;
- Unger, Travis;
- Malunda, Joe;
- Yan Xu;
- Winton, Matthew J.;
- Trojanowski, John Q.;
- Lee, Virginia M.-Y.
Publication type:
Article
Neuroanatomical and cellular degeneration associated with a social disorder characterized by new ritualistic belief systems in a TDP-C patient vs. a Pick patient.
Published in:
Frontiers in Neurology, 2023, p. 01, doi. 10.3389/fneur.2023.1245886
By:
- Ohm, Daniel T.;
- Rhodes, Emma;
- Bahena, Alejandra;
- Capp, Noah;
- Lowe, MaKayla;
- Sabatini, Philip;
- Trotman, Winifred;
- Olm, Christopher A.;
- Phillips, Jeffrey;
- Prabhakaran, Karthik;
- Rascovsky, Katya;
- Massimo, Lauren;
- McMillan, Corey;
- Gee, James;
- Tisdall, M. Dylan;
- Yushkevich, Paul A.;
- Lee, Edward B.;
- Grossman, Murray;
- Irwin, David J.
Publication type:
Article
Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 2, p. 164, doi. 10.1016/j.jalz.2015.07.492
By:
- Montine, Thomas J.;
- Monsell, Sarah E.;
- Beach, Thomas G.;
- Bigio, Eileen H.;
- Bu, Yunqi;
- Cairns, Nigel J.;
- Frosch, Matthew;
- Henriksen, Jonathan;
- Kofler, Julia;
- Kukull, Walter A.;
- Lee, Edward B.;
- Nelson, Peter T.;
- Schantz, Aimee M.;
- Schneider, Julie A.;
- Sonnen, Joshua A.;
- Trojanowski, John Q.;
- Vinters, Harry V.;
- Zhou, Xiao-Hua;
- Hyman, Bradley T.
Publication type:
Article
Relationships of cerebrovascular atherosclerosis with amyloid, tau, α-synuclein and TDP-43 pathologies in neurodegenerative disease dementias
Published in:
2012
By:
- Yarchoan, Mark;
- Xie, Sharon X.;
- Kling, Mitchel A.;
- Toledo, Juan B.;
- Wolk, David A.;
- Lee, Edward B.;
- Van Deerlin, Vivianna M.;
- Virginia, M.-Y. Lee;
- Trojanowski, John Q.;
- Arnold, Steven E.
Publication type:
Abstract
Obesity, leptin, and Alzheimer's disease.
Published in:
Annals of the New York Academy of Sciences, 2011, v. 1243, n. 1, p. 15, doi. 10.1111/j.1749-6632.2011.06274.x
By:
- Lee, Edward B.
Publication type:
Article
BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo.
Published in:
Journal of Cell Biology, 2005, v. 168, n. 2, p. 291, doi. 10.1083/jcb.200407070
By:
- Lee, Edward B.;
- Zhang, Bin;
- Liu, Kangning;
- Greenbaum, Eric A.;
- Doms,, Robert W.;
- Trojanowski, John Q.;
- Lee, Virginia M.-Y.
Publication type:
Article
Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CSF1R p.Arg782His.
Published in:
2015
By:
- Robinson, John L.;
- Suh, EunRan;
- Wood, Elisabeth M.;
- Lee, Edward B.;
- Coslett, H. Branch;
- Raible, Kevin;
- Lee, Virginia M.-Y.;
- Trojanowski, John Q.;
- Van Deerlin, Vivianna M.
Publication type:
Case Study
Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer’s disease.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49205-0
By:
- Ravikumar, Sadhana;
- Denning, Amanda E.;
- Lim, Sydney;
- Chung, Eunice;
- Sadeghpour, Niyousha;
- Ittyerah, Ranjit;
- Wisse, Laura E. M.;
- Das, Sandhitsu R.;
- Xie, Long;
- Robinson, John L.;
- Schuck, Theresa;
- Lee, Edward B.;
- Detre, John A.;
- Tisdall, M. Dylan;
- Prabhakaran, Karthik;
- Mizsei, Gabor;
- de Onzono Martin, Maria Mercedes Iñiguez;
- Arroyo Jiménez, Maria del Mar;
- Mũnoz, Monica;
- Marcos Rabal, Maria del Pilar
Publication type:
Article
Ultrastructure of human brain tissue vitrified from autopsy revealed by cryo-ET with cryo-plasma FIB milling.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47066-1
By:
- Creekmore, Benjamin C.;
- Kixmoeller, Kathryn;
- Black, Ben E.;
- Lee, Edward B.;
- Chang, Yi-Wei
Publication type:
Article
Leveraging spatial transcriptomics data to recover cell locations in single-cell RNA-seq with CeLEry.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39895-3
By:
- Zhang, Qihuang;
- Jiang, Shunzhou;
- Schroeder, Amelia;
- Hu, Jian;
- Li, Kejie;
- Zhang, Baohong;
- Dai, David;
- Lee, Edward B.;
- Xiao, Rui;
- Li, Mingyao
Publication type:
Article
Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141836
By:
- Amlie-Wolf, Alexandre;
- Ryvkin, Paul;
- Tong, Rui;
- Dragomir, Isabelle;
- Suh, EunRan;
- Xu, Yan;
- Van Deerlin, Vivianna M.;
- Gregory, Brian D.;
- Kwong, Linda K.;
- Trojanowski, John Q.;
- Lee, Virginia M.-Y.;
- Wang, Li-San;
- Lee, Edward B.
Publication type:
Article
Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0722-6
By:
- Viaene, Angela N.;
- Lee, Edward B.;
- Rosenbaum, Jason N.;
- Nasrallah, Ilya M.;
- Nasrallah, MacLean P.
Publication type:
Article
Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain.
Published in:
Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0552-y
By:
- Kovacs, Gabor G.;
- Xie, Sharon X.;
- Robinson, John L.;
- Lee, Edward B.;
- Smith, Douglas H.;
- Schuck, Theresa;
- Lee, Virginia M.-Y.;
- Trojanowski, John Q.
Publication type:
Article
Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited.
Published in:
Journal of Neuroscience, 2005, v. 25, n. 9, p. 2386, doi. 10.1523/JNEUROSCI.3089-04.2005
By:
- Lazarov, Orly;
- Morfini, Gerardo A.;
- Lee, Edward B.;
- Farah, Mohamed H.;
- Szodorai, Anita;
- DeBoer, Scott R.;
- Koliatsos, Vassilis E.;
- Kins, Stefan;
- Lee, Virginia M.-Y.;
- Wong, Philip C.;
- Price, Donald L.;
- Brady, Scott T.;
- Sisodia, Sangram S.
Publication type:
Article
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS.
Published in:
BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10538-1
By:
- Pottinger, Tess D.;
- Motelow, Joshua E.;
- Povysil, Gundula;
- Moreno, Cristiane A. Martins;
- Ren, Zhong;
- Phatnani, Hemali;
- Harms, Matthew B.;
- Kwan, Justin;
- Sareen, Dhruv;
- Wang, Han-I.;
- Broach, James R.;
- Simmons, Zachary;
- Arcila-Londono, Ximena;
- Parrott, Steve;
- Lee, Edward B.;
- Deerlin, Vivianna M. Van;
- Fraenkel, Ernest;
- Ostrow, Lyle W.;
- Baas, Frank;
- Zaitlen, Noah
Publication type:
Article
The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis.
Published in:
Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01725-y
By:
- Verheijen, Bert M.;
- Chung, Claire;
- Thompson, Ben;
- Kim, Hyunjin;
- Nakahara, Asa;
- Anink, Jasper J.;
- Mills, James D.;
- NYGC ALS Consortium;
- Phatnani, Hemali;
- Kwan, Justin;
- Sareen, Dhruv;
- Broach, James R.;
- Simmons, Zachary;
- Arcila-Londono, Ximena;
- Lee, Edward B.;
- Van Deerlin, Vivianna M.;
- Shneider, Neil A.;
- Fraenkel, Ernest;
- Ostrow, Lyle W.;
- Baas, Frank
Publication type:
Article

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