We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Structural biology: Translocation chamber's secrets.
- Authors
Christie, Peter J.
- Abstract
The article offers significant information related to DNA transfer across membranes which is considered to be a fundamental life process. It states that the structure of part of a protein channel that performs this task offers insight into the mechanism of DNA passage through bacterial cell envelopes. It discusses the process called conjugation where many bacterial species transfer DNA to neighbouring cells. It adds that conjugation has played a dominant part in shaping bacterial genomes and poses an enormous public-health problem as a mechanism underlying the rapid dissemination of antibiotic-resistance genes and other virulence traits among pathogens.
- Subjects
MICROBIOLOGY; BACTERIAL conjugation; DNA; CELL membranes; PROTEINS; CELLULAR mechanics; BACTERIA; GENOMES; GENES; PATHOGENIC microorganisms
- Publication
Nature, 2009, Vol 462, Issue 7276, p992
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/462992b