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- Title
Nuclear envelope myopathy.
- Authors
Hayashi, Yukiko K.
- Abstract
Nuclear envelope (NE) is a term of the structure surrounding each nucleus of the cell and has many important functions including maintaining chromatin organization. Mutations in the genes encoding NE proteins are known to cause several diseases including myopathies. The age at onset and clinical features of NE myopathy are quite variable, but careful management of associated cardiac symptoms including lethal arrhythmia and cardiomyopathy is critical for the prognosis. In this review, clinical characteristics of NE myopathies together with recent advances of their management is described.
- Subjects
NUCLEAR membranes; MUSCLE diseases; CELL nuclei; ARRHYTHMIA; MUSCULAR dystrophy; AGE of onset; NEMALINE myopathy
- Publication
Neurology & Clinical Neuroscience, 2022, Vol 10, Issue 6, p298
- ISSN
2049-4173
- Publication type
Article
- DOI
10.1111/ncn3.12602