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- Title
Fulminant inflammatory demyelination presenting as stroke‐in‐evolution in an elderly subject.
- Authors
Sacco, Simone; Callegari, Ilaria; Canavero, Isabella; Coloberti, Elisa; Farina, Lisa Maria; Ravaglia, Sabrina; Simoncelli, Anna; Pichiecchio, Anna; Micieli, Giuseppe
- Abstract
Background: Fulminant inflammatory demyelination is a possible presentation of inflammatory demyelinating disorders, thus representing a potential stroke mimic especially in younger patients. Aims of the study: To describe clinical and diagnostic pitfalls in a case of fulminant inflammatory demyelination presenting with stroke‐like symptoms in an elderly patient. Methods: Case report and case‐based review of the literature. Results: A 67‐year‐old woman, who accessed the emergency room as suspect stroke for hyperacute onset of rapidly worsening speech impairment and drowsiness, was later diagnosed with a huge brain inflammatory demyelination. Clinical, laboratory, and neuroimaging tests did not allow to put a more specific diagnosis. Due to the rapidly deteriorating course, she received immunosuppression with benefit. Conclusion: This report is meant to highlight the diagnostic challenges connected with fulminant inflammatory demyelination, which sometime can resemble a stroke‐in evolution and appear clinically unfitting for inclusion in any specific pathological entities within the broad‐spectrum of inflammatory demyelinating disorders.
- Subjects
DEMYELINATION; OLDER people; STROKE; OLDER patients; SYMPTOMS; DIAGNOSIS
- Publication
Brain & Behavior, 2021, Vol 11, Issue 8, p1
- ISSN
2162-3279
- Publication type
Article
- DOI
10.1002/brb3.1967