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- Title
Early panretinal photocoagulation for ERG-verified ischaemic central retinal vein occlusion.
- Authors
Kjeka, Ole; Jansson, Ragnhild W.; Bredrup, Cecilie; Krohn, Jørgen
- Abstract
. Purpose: We have previously shown that photopic cone b-wave implicit time ≥35.0 ms in 30 Hz flicker electroretinography (ERG) predicts ocular neovascularization (NV) in central retinal vein occlusion (CRVO). Here, we evaluate the effects of early panretinal photocoagulation (PRP) in patients with ERG-verified ischaemic CRVO. Methods: Patients with CRVO, admitted to our department between 2000 and 2008, were classified as having ischaemic or non-ischaemic CRVO based on the ERG-results. In a first group of 71 patients, 18 patients had ischaemic CRVO and were assigned to standard treatment that is regular examinations and PRP as soon as NV was found. In a consecutive group of 65 patients, 18 patients with ischaemic CRVO received early PRP. In this group, ERG was performed on average 6 weeks after the first symptoms of CRVO. The patients underwent PRP as soon as possible after the ERG-examination, and the treatment was completed within one to three sessions. Results: Twelve patients in the standard treatment group developed neovascular glaucoma during a mean period of 5 months after the CRVO. In the early treatment group, one patient developed subtle iris rubeosis 7 months after PRP. Otherwise, none of the patients showed any signs of ocular NV, and the intraocular pressure remained within normal range, without the necessity of supplementary medication, during a mean follow-up of 41 months. Conclusions: This study indicates that ocular NV in patients with CRVO can be predicted by photopic 30 Hz flicker ERG and that early PRP in ERG-verified ischaemic CRVO could be suggested as standard treatment.
- Subjects
RETINAL vein; ARTERIAL occlusions; ELECTRORETINOGRAPHY; NEOVASCULARIZATION; LIGHT coagulation; DISEASES
- Publication
Acta Ophthalmologica (1755375X), 2013, Vol 91, Issue 1, p37
- ISSN
1755-375X
- Publication type
Article
- DOI
10.1111/j.1755-3768.2011.02320.x