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- Title
A unique leukoencephalopathy accompanied by palmoplantar pustulosis with identical pathological feature of helper T cell accumulation.
- Authors
Ryo Sasaki; Yoshio Omote; Koh Tadokoro; Namiko Matsumoto; Emi Nomura; Mami Takemoto; Nozomi Hishikawa; Toru Yamashita; Yasuyuki Ohta; Koji Abe
- Abstract
Palmoplantar pustulosis is a chronic inflammatory skin disease involving the palms and soles where mild accumulation of helper T cells and neutrophils in the dermis histologically are observed. Leukoencephalopathy is a brain disease affecting white matter but is rarely accompanied by skin lesion. Here we report a unique case of leukoencephalopathy accompanied by palmoplantar pustulosis with identical pathological feature of helper T cell accumulation in both the brain and skin, suggesting a possible link in the pathogenesis.
- Subjects
T helper cells; PALMOPLANTAR keratoderma; LEUKOENCEPHALOPATHIES; BRAIN diseases
- Publication
Neurology Asia, 2020, Vol 25, Issue 3, p415
- ISSN
1823-6138
- Publication type
Article