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- Title
GIANT CELL LESION OR LANGERHANS' CELL HISTIOCYTOSIS OF THE MANDIBLE? A CASE REPORT.
- Authors
VALENTINI, V.; TERENZI, V.; CASSONI, A.; BOSCO, S.; BRAUNER, E.; SHAHINAS, J.; POMPA, G.
- Abstract
Langerhans' cell histiocytosis (LCH), formerly known as histiocytosis X, is characterized by cell proliferation. The leading clinical symptom of LCH within mandibular and maxillary bones is pain and it may resemble periodontal diseases, apical cysts, ameloblastoma, central giant cell granuloma, vascular malformation, osteomyelitys, bone metastasis and malignancies. In this paper we present the case of a mandibular histiocytosis misdiagnosed as a reparative giant cell granuloma at the first and as an aggressive giant cell tumor at the second biopsy. Definitive diagnosis was made only after examination of surgical specimens following hemimandibulectomy.
- Subjects
LANGERHANS cells; MANDIBLE abnormalities; LANGERHANS-cell histiocytosis; PERIODONTAL disease; AMELOBLASTOMA; BIOPSY; BONE metastasis
- Publication
European Journal of Inflammation, 2012, Vol 10, Issue 1, p159
- ISSN
1721-727X
- Publication type
Article
- DOI
10.1177/1721727X1201000122