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Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C-Labeled Molecular Probe.
Published in:
Angewandte Chemie, 2016, v. 128, n. 36, p. 10784, doi. 10.1002/ange.201603731
By:
- Nishihara, Tatsuya;
- Yoshihara, Hikari A. I.;
- Nonaka, Hiroshi;
- Takakusagi, Yoichi;
- Hyodo, Fuminori;
- Ichikawa, Kazuhiro;
- Can, Emine;
- Bastiaansen, Jessica A. M.;
- Takado, Yuhei;
- Comment, Arnaud;
- Sando, Shinsuke
Publication type:
Article
Strategies for Utilizing Neuroimaging Biomarkers in CNS Drug Discovery and Development: CINP/JSNP Working Group Report.
Published in:
International Journal of Neuropsychopharmacology, 2017, v. 20, n. 4, p. 285, doi. 10.1093/ijnp/pyw111
By:
- Tetsuya Suhara;
- Shigeyuki Chaki;
- Haruhide Kimura;
- Makoto Furusawa;
- Mitsuyuki Matsumoto;
- Hiroo Ogura;
- Takaaki Negishi;
- Takeaki Saijo;
- Makoto Higuchi;
- Tomohiro Omura;
- Rira Watanabe;
- Sosuke Miyoshi;
- Noriaki Nakatani;
- Noboru Yamamoto;
- Shyh-Yuh Liou;
- Yuhei Takado;
- Jun Maeda;
- Yasumasa Okamoto;
- Yoshiaki Okubo;
- Makiko Yamada
Publication type:
Article
Alterations of striatal phosphodiesterase 10 A and their association with recurrence rate in bipolar I disorder.
Published in:
Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-03107-3
By:
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Kubota, Manabu;
- Moriguchi, Sho;
- Matsuoka, Kiwamu;
- Kurose, Shin;
- Tagai, Kenji;
- Endo, Hironobu;
- Yamagata, Bun;
- Suzuki, Hisaomi;
- Tarumi, Ryosuke;
- Nomoto, Kie;
- Takado, Yuhei;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Tabuchi, Hajime;
- Mimura, Masaru;
- Uchida, Hiroyuki;
- Higuchi, Makoto;
- Takahata, Keisuke
Publication type:
Article
Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C-Labeled Molecular Probe.
Published in:
Angewandte Chemie International Edition, 2016, v. 55, n. 36, p. 10626, doi. 10.1002/anie.201603731
By:
- Nishihara, Tatsuya;
- Yoshihara, Hikari A. I.;
- Nonaka, Hiroshi;
- Takakusagi, Yoichi;
- Hyodo, Fuminori;
- Ichikawa, Kazuhiro;
- Can, Emine;
- Bastiaansen, Jessica A. M.;
- Takado, Yuhei;
- Comment, Arnaud;
- Sando, Shinsuke
Publication type:
Article
Positron Emission Tomography Assessments of Phosphodiesterase 10A in Patients With Schizophrenia.
Published in:
Schizophrenia Bulletin, 2023, v. 49, n. 3, p. 688, doi. 10.1093/schbul/sbac181
By:
- Kubota, Manabu;
- Takahata, Keisuke;
- Matsuoka, Kiwamu;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Tagai, Kenji;
- Tarumi, Ryosuke;
- Suzuki, Hisaomi;
- Kurose, Shin;
- Nakajima, Shinichiro;
- Shiwaku, Hiroki;
- Seki, Chie;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Takahashi, Hidehiko;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
In vivo characterization of tau accumulation in patients with frontotemporal dementia: A PET study with 18F‐florzolotau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078492
By:
- Kubota, Manabu;
- Endo, Hironobu;
- Takahata, Keisuke;
- Tagai, Kenji;
- Suzuki, Hisaomi;
- Onaya, Mitsumoto;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Kurose, Shin;
- Matsuoka, Kiwamu;
- Seki, Chie;
- Shinotoh, Hitoshi;
- Kawamura, Kazunori;
- Zhang, Ming‐Rong;
- Takado, Yuhei;
- Shimada, Hitoshi;
- Higuchi, Makoto
Publication type:
Article
Development and Comparison of a Novel Mid‐Region Directed p‐Tau 181 Assay with Tau Positron Emission Tomography in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078621
By:
- Tagai, Kenji;
- Tatebe, Harutsugu;
- Matsuura, Sayo;
- Zhang, Hong;
- Kokubo, Naomi;
- Matsuoka, Kiwamu;
- Endo, Hironobu;
- Oyama, Asaka;
- Hirata, Kosei;
- Shinotoh, Hitoshi;
- Kataoka, Yuko;
- Matsumoto, Hideki;
- Oya, Masaki;
- Kurose, Shin;
- Takahata, Keisuke;
- Ichihashi, Masanori;
- Kubota, Manabu;
- Seki, Chie;
- Shimada, Hitoshi;
- Takado, Yuhei
Publication type:
Article
CenTauRz: A standardized quantification of tau PET scans.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.061171
By:
- Dore, Vincent;
- Bullich, Santiago;
- Bohorquez, Sandra Sanabria;
- Leuzy, Antoine;
- Shimada, Hitoshi;
- Rowe, Christopher C.;
- Bourgeat, Pierrick;
- Lopresti, Brian J.;
- Huang, Kun;
- Krishnadas, Natasha;
- Fripp, Jurgen;
- Takado, Yuhei;
- Stephens, Andrew W.;
- Weimer, Robby;
- Higuchi, Makoto;
- Hansson, Oskar;
- Villemagne, Victor L
Publication type:
Article
Altered brain energy metabolism related to astrocytes in tauopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.059834
By:
- Hirata, Kosei;
- Matsuoka, Kiwamu;
- Tagai, Kenji;
- Endo, Hironobu;
- Kokubo, Naomi;
- Tatebe, Harutsugu;
- Zhang, Hong;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Ono, Maiko;
- Obata, Takayuki;
- Kawamura, Kazunori;
- Zhang, Ming‐Rong;
- Shimada, Hitoshi;
- Tokuda, Takahiko;
- Yokota, Takanori;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
CenTauRz: A standardized quantification of tau PET scans.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.061177
By:
- Dore, Vincent;
- Bullich, Santiago;
- Bohorquez, Sandra Sanabria;
- Leuzy, Antoine;
- Shimada, Hitoshi;
- Rowe, Christopher;
- Bourgeat, Pierrick;
- Lopresti, Brian J;
- Huang, Kun;
- Krishnadas, Natasha;
- Fripp, Jurgen;
- Takado, Yuhei;
- Stephens, Andrew W;
- Weimer, Robby;
- Higuchi, Makoto;
- Hansson, Oskar;
- Villemagne, Victor L
Publication type:
Article
Towards a universal cortical tau sampling mask.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055816
By:
- Dore, Vincent;
- Bohorquez, Sandra Sanabria;
- Leuzy, Antoine;
- Shimada, Hitoshi;
- Bullich, Santiago;
- Bourgeat, Pierrick;
- Burnham, Samantha C;
- Huang, Kun;
- Krishnadas, Natasha;
- Fripp, Jurgen;
- Takado, Yuhei;
- Stephens, Andrew W;
- Weimer, Robby;
- Rowe, Christopher C;
- Higuchi, Makoto;
- Hansson, Oskar;
- Villemagne, Victor L
Publication type:
Article
A tau PET study of primary age‐related tauopathy in healthy volunteers: Neuroimaging / Normal brain aging.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041730
By:
- Shinotoh, Hitoshi;
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Matsuoka, Kiwamu;
- Takado, Yuhei;
- Nakano, Yoshikazu;
- Hirano, Shigeki;
- Zhang, Ming‐Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Activation of Nav1.1 ameliorates tau pathology and brain atrophy in a mouse model of tauopathy: Nonhuman/Target identification and validation studies: Tau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038201
By:
- Sampei, Kazuaki;
- Seki, Chie;
- Takuwa, Hiroyuki;
- Maeda, Jun;
- Ono, Maiko;
- Tokunaga, Masaki;
- Shimojo, Masafumi;
- Honda, Shigeyuki;
- Kimura, Taeko;
- Ishikawa, Taizo;
- Kudo, Takehiro;
- Takado, Yuhei;
- Sahara, Naruhiko;
- Higuchi, Makoto
Publication type:
Article
Tau‐induced brain atrophy and neuroinflammation accelerated by low‐protein diet and decelerated by selected essential amino acids in a murine model of tauopathies: Molecular and cell biology/neurodegeneration and neuroprotection.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037539
By:
- Takado, Yuhei;
- Sato, Hideaki;
- Tsukamoto‐Yasui, Masako;
- Minatohara, Keiichiro;
- Takahashi, Manami;
- Urushihata, Takuya;
- Takuwa, Hiroyuki;
- Ono, Maiko;
- Maeda, Jun;
- Sahara, Naruhiko;
- Aoki, Ichio;
- Toyoda, Sakiko;
- Karakawa, Sachise;
- Isokawa, Muneki;
- Kawasaki, Noriko;
- Ueno, Satoko;
- Kanda, Mayuka;
- Nishimura, Mai;
- Suzuki, Katsuya;
- Mitsui, Akira
Publication type:
Article
P4‐586: CLINICAL CHARACTERIZATION OF [18F]PM‐PBB3 IN THE BRAINS OF MILD‐REPETITIVE TRAUMATIC BRAIN INJURY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1546, doi. 10.1016/j.jalz.2019.08.134
By:
- Takahata, Keisuke;
- Sahara, Naruhiko;
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takado, Yuhei;
- Seki, Chie;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Kuramochi, Shin;
- Mizushima, Jin;
- Anamizu, Sachiko;
- Tabuchi, Hajime;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Mimura, Masaru;
- Higuchi, Makoto
Publication type:
Article
P2‐382: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P749, doi. 10.1016/j.jalz.2019.06.2789
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
IC‐P‐179: IN VIVO TRACKING OF TAU PATHOLOGIES WITH 18F‐PM‐PBB3 (18F‐APN‐1607) PET IN AD AND DIVERSE NON‐AD TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P140, doi. 10.1016/j.jalz.2019.06.4294
By:
- Shimada, Hitoshi;
- Tagai, Kenji;
- Kubota, Manabu;
- Takahata, Keisuke;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Yamamoto, Yasuharu;
- Sano, Yasunori;
- Seki, Chie;
- Hirano, Shigeki;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Ono, Maiko;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Sahara, Naruhiko;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Kuwabara, Satoshi;
- Hattori, Nobutaka
Publication type:
Article
P1‐125: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P318, doi. 10.1016/j.jalz.2018.06.128
By:
- Shimada, Hitoshi;
- Ono, Maiko;
- Tagai, Kenji;
- Kubota, Manabu;
- Kitamura, Soichiro;
- Takuwa, Hiroyuki;
- Seki, Chie;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Yamamoto, Naoyoshi;
- Sano, Yasunori;
- Takado, Yuhei;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Marek, Kenneth
Publication type:
Article
IC‐P‐221: TAU ACCUMULATION PREDICTS PROGRESSION OF DEMENTIA IN SUBJECTS WITH EARLY ALZHEIMER'S DISEASE IN THE ALZHEIMER'S DISEASE SPECTRUM: A [11C]PBB3 POSITRON EMISSION TOMOGRAPHY STUDY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P180, doi. 10.1016/j.jalz.2018.06.2288
By:
- Tagai, Kenji;
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- Takahata, Keisuke;
- Kubota, Manabu;
- Takado, Yuhei;
- Shinotoh, Hitoshi;
- Nakano, Yoshikazu;
- Ishii, Tatsuya;
- Hirano, Shigeki;
- Shigeta, Masahiro;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
IC‐P‐217: PRECLINICAL AND CLINICAL CHARACTERIZATION OF 18F‐PM‐PBB3, A PET LIGAND FOR DIVERSE TAU PATHOLOGIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P177, doi. 10.1016/j.jalz.2018.06.2284
By:
- Shimada, Hitoshi;
- Ono, Maiko;
- Tagai, Kenji;
- Kubota, Manabu;
- Kitamura, Soichiro;
- Takuwa, Hiroyuki;
- Seki, Chie;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Yamamoto, Naoyoshi;
- Sano, Yasunori;
- Takado, Yuhei;
- Tempest, Paul;
- Jang, Ming-Kuei;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Marek, Kenneth
Publication type:
Article
Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-27653-w
By:
- Hashimoto, Shoko;
- Matsuba, Yukio;
- Takahashi, Mika;
- Kamano, Naoko;
- Watamura, Naoto;
- Sasaguri, Hiroki;
- Takado, Yuhei;
- Yoshihara, Yoshihiro;
- Saito, Takashi;
- Saido, Takaomi C.
Publication type:
Article
Imaging of Neuronal Activity in Awake Mice by Measurements of Flavoprotein Autofluorescence Corrected for Cerebral Blood Flow.
Published in:
Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2017.00723
By:
- Takahashi, Manami;
- Urushihata, Takuya;
- Takuwa, Hiroyuki;
- Sakata, Kazumi;
- Takado, Yuhei;
- Shimizu, Eiji;
- Suhara, Tetsuya;
- Higuchi, Makoto;
- Ito, Hiroshi
Publication type:
Article
A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains.
Published in:
EMBO Journal, 2021, v. 40, n. 22, p. 1, doi. 10.15252/embj.2021107757
By:
- Shimojo, Masafumi;
- Ono, Maiko;
- Takuwa, Hiroyuki;
- Mimura, Koki;
- Nagai, Yuji;
- Fujinaga, Masayuki;
- Kikuchi, Tatsuya;
- Okada, Maki;
- Seki, Chie;
- Tokunaga, Masaki;
- Maeda, Jun;
- Takado, Yuhei;
- Takahashi, Manami;
- Minamihisamatsu, Takeharu;
- Zhang, Ming‐Rong;
- Tomita, Yutaka;
- Suzuki, Norihiro;
- Maximov, Anton;
- Suhara, Tetsuya;
- Minamimoto, Takafumi
Publication type:
Article
FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P146, doi. 10.1016/j.jalz.2017.06.2573
By:
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- Ono, Maiko;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Takahata, Keisuke;
- Moriguchi, Sho;
- Kubota, Manabu;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Seki, Chie;
- Hirano, Shigeki;
- Shinotoh, Hitoshi;
- Sahara, Naruhiko;
- Tempest, Paul;
- Tamagnan, Gilles;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Zhang, Ming-Rong
Publication type:
Article
FIRST-IN-HUMAN PET STUDY WITH 18F-AM-PBB3 AND 18F-PM-PBB3.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1104, doi. 10.1016/j.jalz.2017.06.1594
By:
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- ONO, Maiko;
- Kimura, Yasuyuki;
- Ichise, Masanori;
- Takahata, Keisuke;
- Moriguchi, Sho;
- Kubota, Manabu;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Seki, Chie;
- Hirano, Shigeki;
- Shinotoh, Hitoshi;
- Sahara, Naruhiko;
- Tempest, Paul;
- Tamagnan, Gilles;
- Seibyl, John;
- Barret, Olivier;
- Alagille, David;
- Zhang, Ming-Rong
Publication type:
Article
Neurometabolite Levels and Relevance to Central Sensitization in Chronic Orofacial Pain Patients: A Magnetic Resonance Spectroscopy Study.
Published in:
Journal of Pain Research, 2022, v. 15, p. 1421, doi. 10.2147/JPR.S362793
By:
- Terumitsu, Makoto;
- Takado, Yuhei;
- Fukuda, Ken-Ichi;
- Kato, Eisuke;
- Tanaka, Sei
Publication type:
Article
Intraocular Water Movement Visualization Using 1H‐MRI With Eye Drops of O‐17‐Labeled Saline: First‐in‐Human Study.
Published in:
Journal of Magnetic Resonance Imaging, 2023, v. 57, n. 3, p. 845, doi. 10.1002/jmri.28345
By:
- Tomiyasu, Moyoko;
- Sahara, Yasuka;
- Mitsui, Etsuko;
- Tsuchiya, Hiroki;
- Maeda, Takamasa;
- Tomoyori, Nobuhiro;
- Kawashima, Makoto;
- Nogawa, Toshifumi;
- Kishimoto, Riwa;
- Takado, Yuhei;
- Higashi, Tatsuya;
- Mizota, Atsushi;
- Kudo, Kohsuke;
- Obata, Takayuki
Publication type:
Article
Hyperpolarized C lactate as a substrate for in vivo metabolic studies in skeletal muscle.
Published in:
Metabolomics, 2014, v. 10, n. 5, p. 986, doi. 10.1007/s11306-014-0630-5
By:
- Bastiaansen, Jessica;
- Yoshihara, Hikari;
- Takado, Yuhei;
- Gruetter, Rolf;
- Comment, Arnaud
Publication type:
Article
MRS-measured glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 1, p. 197, doi. 10.1177/0271678X211045449
By:
- Takado, Yuhei;
- Takuwa, Hiroyuki;
- Sampei, Kazuaki;
- Urushihata, Takuya;
- Takahashi, Manami;
- Shimojo, Masafumi;
- Uchida, Shoko;
- Nitta, Nobuhiro;
- Shibata, Sayaka;
- Nagashima, Keisuke;
- Ochi, Yoshihiro;
- Ono, Maiko;
- Maeda, Jun;
- Tomita, Yutaka;
- Sahara, Naruhiko;
- Near, Jamie;
- Aoki, Ichio;
- Shibata, Kazuhisa;
- Higuchi, Makoto
Publication type:
Article
Dynamic alterations in the central glutamatergic status following food and glucose intake: in vivo multimodal assessments in humans and animal models.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 11, p. 2928, doi. 10.1177/0271678X211004150
By:
- Kubota, Manabu;
- Kimura, Yasuyuki;
- Shimojo, Masafumi;
- Takado, Yuhei;
- Duarte, Joao MN;
- Takuwa, Hiroyuki;
- Seki, Chie;
- Shimada, Hitoshi;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Kitamura, Soichiro;
- Moriguchi, Sho;
- Tagai, Kenji;
- Obata, Takayuki;
- Nakahara, Jin;
- Tomita, Yutaka;
- Tokunaga, Masaki;
- Maeda, Jun;
- Kawamura, Kazunori;
- Zhang, Ming-Rong
Publication type:
Article
A human PET study of [C]HMS011, a potential radioligand for AMPA receptors.
Published in:
EJNMMI Research, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13550-017-0313-0
By:
- Takahata, Keisuke;
- Kimura, Yasuyuki;
- Seki, Chie;
- Tokunaga, Masaki;
- Ichise, Masanori;
- Kawamura, Kazunori;
- Ono, Maiko;
- Kitamura, Soichiro;
- Kubota, Manabu;
- Moriguchi, Sho;
- Ishii, Tatsuya;
- Takado, Yuhei;
- Niwa, Fumitoshi;
- Endo, Hironobu;
- Nagashima, Tomohisa;
- Ikoma, Yoko;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Higuchi, Makoto
Publication type:
Article
Case report: Saccadic ping-pong gaze in progressive supranuclear palsy with predominant postural instability.
Published in:
Frontiers in Neurology, 2023, v. 14, p. 01, doi. 10.3389/fneur.2023.1100931
By:
- Hikari Nunomura;
- Taketoshi Kasahara;
- Taku Hatano;
- Hitoshi Shimada;
- Yuhei Takado;
- Hironobu Endo;
- Ayako Inoshita;
- Atsuko Inomata;
- Toshihisa Murofushi;
- Shihoko Misawa;
- Yutaka Machida;
- Hisamasa Imai
Publication type:
Article
Characterization of the mutant β-subunit of β-hexosaminidase for dimer formation responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype.
Published in:
Journal of Biochemistry, 2013, v. 153, n. 1, p. 111, doi. 10.1093/jb/mvs131
By:
- Yamada, Kenichiro;
- Takado, Yuhei;
- Kato, Yusuke S.;
- Yamada, Yasukazu;
- Ishiguro, Hideaki;
- Wakamatsu, Nobuaki
Publication type:
Article
In vivo PET classification of tau pathologies in patients with frontotemporal dementia.
Published in:
Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae075
By:
- Kubota, Manabu;
- Endo, Hironobu;
- Takahata, Keisuke;
- Tagai, Kenji;
- Suzuki, Hisaomi;
- Onaya, Mitsumoto;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Kurose, Shin;
- Matsuoka, Kiwamu;
- Seki, Chie;
- Shinotoh, Hitoshi;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Takado, Yuhei;
- Shimada, Hitoshi;
- Higuchi, Makoto
Publication type:
Article
Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study.
Published in:
Cerebral Cortex, 2020, v. 30, n. 12, p. 6458, doi. 10.1093/cercor/bhaa211
By:
- Kubota, Manabu;
- Fujino, Junya;
- Tei, Shisei;
- Takahata, Keisuke;
- Matsuoka, Kiwamu;
- Tagai, Kenji;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Shimada, Hitoshi;
- Takado, Yuhei;
- Seki, Chie;
- Itahashi, Takashi;
- Aoki, Yuta Y;
- Ohta, Haruhisa;
- Hashimoto, Ryu-ichiro;
- Zhang, Ming-Rong;
- Suhara, Tetsuya;
- Nakamura, Motoaki;
- Takahashi, Hidehiko;
- Kato, Nobumasa
Publication type:
Article
Diffuse Brain Abnormalities in Myotonic Dystrophy Type 1 Detected by 3.0 T Proton Magnetic Resonance Spectroscopy.
Published in:
European Neurology, 2015, v. 73, n. 3/4, p. 247, doi. 10.1159/000371575
By:
- Takado, Yuhei;
- Terajima, Kenshi;
- Ohkubo, Masaki;
- Okamoto, Kouichirou;
- Shimohata, Takayoshi;
- Nishizawa, Masatoyo;
- Igarashi, Hironaka;
- Nakada, Tsutomu
Publication type:
Article
Altered Brain Energy Metabolism Related to Astrocytes in Alzheimer's Disease.
Published in:
Annals of Neurology, 2024, v. 95, n. 1, p. 104, doi. 10.1002/ana.26797
By:
- Hirata, Kosei;
- Matsuoka, Kiwamu;
- Tagai, Kenji;
- Endo, Hironobu;
- Tatebe, Harutsugu;
- Ono, Maiko;
- Kokubo, Naomi;
- Oyama, Asaka;
- Shinotoh, Hitoshi;
- Takahata, Keisuke;
- Obata, Takayuki;
- Dehghani, Masoumeh;
- Near, Jamie;
- Kawamura, Kazunori;
- Zhang, Ming‐Rong;
- Shimada, Hitoshi;
- Yokota, Takanori;
- Tokuda, Takahiko;
- Higuchi, Makoto;
- Takado, Yuhei
Publication type:
Article
High-Contrast Imaging of α-Synuclein Pathologies in Living Patients with Multiple System Atrophy.
Published in:
2022
By:
- Matsuoka, Kiwamu;
- Ono, Maiko;
- Takado, Yuhei;
- Hirata, Kosei;
- Endo, Hironobu;
- Ohfusa, Toshiyuki;
- Kojima, Taichi;
- Yamamoto, Takeshi;
- Onishi, Tomohiro;
- Orihara, Asumi;
- Tagai, Kenji;
- Takahata, Keisuke;
- Seki, Chie;
- Shinotoh, Hitoshi;
- Kawamura, Kazunori;
- Shimizu, Hiroshi;
- Shimada, Hitoshi;
- Kakita, Akiyoshi;
- Zhang, Ming‐Rong;
- Suhara, Tetsuya
Publication type:
Letter
CenTauR: Toward a universal scale and masks for standardizing tau imaging studies.
Published in:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023, v. 15, n. 3, p. 1, doi. 10.1002/dad2.12454
By:
- Villemagne, Victor L.;
- Leuzy, Antoine;
- Bohorquez, Sandra Sanabria;
- Bullich, Santiago;
- Shimada, Hitoshi;
- Rowe, Christopher C.;
- Bourgeat, Pierrick;
- Lopresti, Brian;
- Huang, Kun;
- Krishnadas, Natasha;
- Fripp, Jurgen;
- Takado, Yuhei;
- Gogola, Alexandra;
- Minhas, Davneet;
- Weimer, Robby;
- Higuchi, Makoto;
- Stephens, Andrew;
- Hansson, Oskar;
- Doré, Vincent
Publication type:
Article
Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model.
Published in:
Journal of Neuroscience, 2020, v. 40, n. 17, p. 3491, doi. 10.1523/JNEUROSCI.2880-19.2020
By:
- Masafumi Shimojo;
- Hiroyuki Takuwa;
- Yuhei Takado;
- Masaki Tokunaga;
- Satoshi Tsukamoto;
- Keiichiro Minatohara;
- Maiko Ono;
- Chie Seki;
- Jun Maeda;
- Takuya Urushihata;
- Takeharu Minamihisamatsu;
- Ichio Aoki;
- Kazunori Kawamura;
- Ming-Rong Zhang;
- Tetsuya Suhara;
- Naruhiko Sahara;
- Makoto Higuchi
Publication type:
Article
A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease.
Published in:
Translational Neurodegeneration, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40035-024-00439-4
By:
- Tagai, Kenji;
- Tatebe, Harutsugu;
- Matsuura, Sayo;
- Hong, Zhang;
- Kokubo, Naomi;
- Matsuoka, Kiwamu;
- Endo, Hironobu;
- Oyama, Asaka;
- Hirata, Kosei;
- Shinotoh, Hitoshi;
- Kataoka, Yuko;
- Matsumoto, Hideki;
- Oya, Masaki;
- Kurose, Shin;
- Takahata, Keisuke;
- Ichihashi, Masanori;
- Kubota, Manabu;
- Seki, Chie;
- Shimada, Hitoshi;
- Takado, Yuhei
Publication type:
Article
Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study.
Published in:
Movement Disorders, 2011, v. 26, n. 7, p. 1297, doi. 10.1002/mds.23550
By:
- Takado, Yuhei;
- Igarashi, Hironaka;
- Terajima, Kenshi;
- Shimohata, Takayoshi;
- Ozawa, Tetsutaro;
- Okamoto, Kouichirou;
- Nishizawa, Masatoyo;
- Nakada, Tsutomu
Publication type:
Article
Megacolon in multiple system atrophy: Safety concerns related to PEG.
Published in:
Movement Disorders, 2009, v. 24, n. 7, p. 1096, doi. 10.1002/mds.22281
By:
- Tezuka, Toshiyuki;
- Ozawa, Tetsutaro;
- Takado, Yuhei;
- Sato, Yuichi;
- Oyake, Mutsuo;
- Nishizawa, Masatoyo
Publication type:
Article
New mutation in the non-gigantic exon of SACS in Japanese siblings.
Published in:
Movement Disorders, 2007, v. 22, n. 5, p. 748, doi. 10.1002/mds.21365
By:
- Takado, Yuhei;
- Hara, Kenju;
- Shimohata, Takayoshi;
- Tokiguchi, Susumu;
- Onodera, Osamu;
- Nishizawa, Masatoyo
Publication type:
Article
A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 13, p. 4298, doi. 10.1007/s00259-022-05898-3
By:
- Kimura, Taeko;
- Ono, Maiko;
- Seki, Chie;
- Sampei, Kazuaki;
- Shimojo, Masafumi;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Sahara, Naruhiko;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
Correction to: First‑in‑human in vivo imaging and quantification of monoacylglycerol lipase in the brain: a PET study with 18F‑T‑401.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 9, p. 3299, doi. 10.1007/s00259-022-05795-9
By:
- Takahata, Keisuke;
- Seki, Chie;
- Kimura, Yasuyuki;
- Kubota, Manabu;
- Ichise, Masanori;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Tagai, Kenji;
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- Matsuoka, Kiwamu;
- Endo, Hironobu;
- Shinotoh, Hitoshi;
- Kawamura, Kazunori;
- Zhang, Ming‑Rong;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
First-in-human in vivo imaging and quantification of monoacylglycerol lipase in the brain: a PET study with 18F-T-401.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 9, p. 3150, doi. 10.1007/s00259-021-05671-y
By:
- Takahata, Keisuke;
- Seki, Chie;
- Kimura, Yasuyuki;
- Kubota, Manabu;
- Ichise, Masanori;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Tagai, Kenji;
- Shimada, Hitoshi;
- Kitamura, Soichiro;
- Matsuoka, Kiwamu;
- Endo, Hironobu;
- Shinotoh, Hitoshi;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Takado, Yuhei;
- Higuchi, Makoto
Publication type:
Article
A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 7.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 9, p. 2846, doi. 10.1007/s00259-021-05235-0
By:
- Kubota, Manabu;
- Seki, Chie;
- Kimura, Yasuyuki;
- Takahata, Keisuke;
- Shimada, Hitoshi;
- Takado, Yuhei;
- Matsuoka, Kiwamu;
- Tagai, Kenji;
- Sano, Yasunori;
- Yamamoto, Yasuharu;
- Okada, Maki;
- Kikuchi, Tatsuya;
- Ichise, Masanori;
- Kawamura, Kazunori;
- Zhang, Ming-Rong;
- Higuchi, Makoto
Publication type:
Article
Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy.
Published in:
Aging Cell, 2022, v. 21, n. 7, p. 1, doi. 10.1111/acel.13615
By:
- Ono, Maiko;
- Komatsu, Masaaki;
- Ji, Bin;
- Takado, Yuhei;
- Shimojo, Masafumi;
- Minamihisamatsu, Takeharu;
- Warabi, Eiji;
- Yanagawa, Toru;
- Matsumoto, Gen;
- Aoki, Ichio;
- Kanaan, Nicholas M.;
- Suhara, Tetsuya;
- Sahara, Naruhiko;
- Higuchi, Makoto
Publication type:
Article

Found: 52