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Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 51, p. 15410, doi. 10.1002/anie.201508416
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- Publication type:
- Article
Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites.
- Published in:
- Nucleic Acids Research, 2018, v. 46, n. 5, p. 2398, doi. 10.1093/nar/gkx1303
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- Publication type:
- Article
High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 19, p. 9017, doi. 10.1093/nar/gkw783
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- Publication type:
- Article
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 8, p. 5059, doi. 10.1093/nar/gku095
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- Publication type:
- Article
Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase.
- Published in:
- Nucleic Acids Research, 2010, v. 38, n. 1, p. 82, doi. 10.1093/nar/gkp873
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- Publication type:
- Article
A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 14, p. 4000, doi. 10.1093/nar/gkl505
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- Publication type:
- Article
Structure‐Guided Synthesis and Evaluation of Small‐Molecule Inhibitors Targeting Protein–Protein Interactions of BRCA1 tBRCT Domain.
- Published in:
- ChemMedChem, 2019, v. 14, n. 18, p. 1620, doi. 10.1002/cmdc.201900300
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- Publication type:
- Article
A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1191, doi. 10.1038/nsmb.2666
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- Publication type:
- Article
Cell-cycle coordination between DNA replication and recombination revealed by a vertebrate N-end rule degron-Rad51.
- Published in:
- Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1049, doi. 10.1038/nsmb.1490
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- Publication type:
- Article
PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.
- Published in:
- Nature Structural & Molecular Biology, 2004, v. 11, n. 11, p. 1114, doi. 10.1038/nsmb837
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- Publication type:
- Article
Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 51, p. 15630, doi. 10.1002/ange.201508416
- By:
- Publication type:
- Article
From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1.
- Published in:
- Angewandte Chemie, 2011, v. 123, n. 17, p. 4089, doi. 10.1002/ange.201008019
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- Publication type:
- Article
Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents.
- Published in:
- Scientific Reports, 2016, p. 29741, doi. 10.1038/srep29741
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- Publication type:
- Article
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
- Published in:
- Scientific Reports, 2016, p. 28528, doi. 10.1038/srep28528
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- Publication type:
- Article
A transcriptional response to replication stress selectively expands a subset of Brca2-mutant mammary epithelial cells.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40956-w
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- Publication type:
- Article
Maximizing the Biochemical Resolving Power of Fluorescence Microscopy.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077392
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- Publication type:
- Article
A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0061893
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- Publication type:
- Article
Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA damage and mitotic progression.
- Published in:
- Oncogene, 2004, v. 23, n. 4, p. 865, doi. 10.1038/sj.onc.1207223
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- Publication type:
- Article
Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia.
- Published in:
- Cancers, 2022, v. 14, n. 4, p. 963, doi. 10.3390/cancers14040963
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- Publication type:
- Article
Linear Aliphatic Dialkynes as Alternative Linkers for Double-Click Stapling of p53-Derived Peptides.
- Published in:
- ChemBioChem, 2014, v. 15, n. 18, p. 2680, doi. 10.1002/cbic.201402374
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- Publication type:
- Article
Using a Fragment-Based Approach To Target Protein-Protein Interactions.
- Published in:
- ChemBioChem, 2013, v. 14, n. 3, p. 332, doi. 10.1002/cbic.201200521
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- Publication type:
- Article
The seroepidemiology of infection due to Epstein-Barr virus in southern India.
- Published in:
- Journal of Medical Virology, 1985, v. 15, n. 1, p. 11, doi. 10.1002/jmv.1890150103
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- Publication type:
- Article
Cancer: Let sleeping DNA lie.
- Published in:
- 2011
- By:
- Publication type:
- Opinion
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response.
- Published in:
- 2008
- By:
- Publication type:
- Letter
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50702-2
- By:
- Publication type:
- Article
The GDI-like solubilizing factor PDE? sustains the spatial organization and signalling of Ras family proteins.
- Published in:
- 2012
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- Publication type:
- Correction Notice
The GDI-like solubilizing factor PDE? sustains the spatial organization and signalling of Ras family proteins.
- Published in:
- Nature Cell Biology, 2012, v. 14, n. 2, p. 148, doi. 10.1038/ncb2394
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- Publication type:
- Article
A mitotic role for the DNA damage-responsive CHK2 kinase.
- Published in:
- Nature Cell Biology, 2010, v. 12, n. 5, p. 424, doi. 10.1038/ncb0510-424
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- Publication type:
- Article
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.
- Published in:
- Nature Cell Biology, 2009, v. 11, n. 11, p. 1363, doi. 10.1038/ncb1983
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- Publication type:
- Article
DUBing down a tumour suppressor.
- Published in:
- Nature Cell Biology, 2005, v. 7, n. 4, p. 332, doi. 10.1038/ncb0405-332
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- Publication type:
- Article
Expression of LY6 D is induced at the surface of MCF10A cells by X-ray irradiation.
- Published in:
- FEBS Journal, 2012, v. 279, n. 24, p. 4479, doi. 10.1111/febs.12034
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- Publication type:
- Article
Interrogation of the Protein-Protein Interactions between Human BRCA2 BRC Repeats and RAD51 Reveals Atomistic Determinants of Affinity.
- Published in:
- PLoS Computational Biology, 2011, v. 7, n. 7, p. 1, doi. 10.1371/journal.pcbi.1002096
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- Publication type:
- Article
Computational Analysis of Phosphopeptide Binding to the Polo-Box Domain of the Mitotic Kinase PLK1 Using Molecular Dynamics Simulation.
- Published in:
- PLoS Computational Biology, 2010, v. 6, n. 8, p. 1, doi. 10.1371/journal.pcbi.1000880
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- Publication type:
- Article
Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.
- Published in:
- Nature Communications, 2014, v. 5, n. 6, p. 4048, doi. 10.1038/ncomms5048
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- Publication type:
- Article
Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.
- Published in:
- Nature Communications, 2014, v. 5, n. 1, p. 3155, doi. 10.1038/ncomms4155
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- Publication type:
- Article
Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength.
- Published in:
- Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-015-0749-3
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- Publication type:
- Article
Medicine: Aborting the birth of cancer.
- Published in:
- Nature, 2005, v. 434, n. 7035, p. 829, doi. 10.1038/434829a
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- Publication type:
- Article
Insights into DNA recombination from the structure of a RAD51–BRCA2 complex.
- Published in:
- Nature, 2002, v. 420, n. 6913, p. 287, doi. 10.1038/nature01230
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- Publication type:
- Article
A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission.
- Published in:
- Journal of Cell Biology, 2011, v. 192, n. 6, p. 969, doi. 10.1083/jcb.201008125
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- Publication type:
- Article
Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.
- Published in:
- Nucleic Acids Research, 2021, v. 49, n. 10, p. 5588, doi. 10.1093/nar/gkab308
- By:
- Publication type:
- Article
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 14, p. 7844, doi. 10.1093/nar/gkaa570
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- Publication type:
- Article
Palladium-Catalysed Cross-Coupling of Vinyldisiloxanes with Benzylic and Allylic Halides and Sulfonates.
- Published in:
- Chemistry - A European Journal, 2012, v. 18, n. 28, p. 8774, doi. 10.1002/chem.201200431
- By:
- Publication type:
- Article
Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor.
- Published in:
- Nature, 1998, v. 391, n. 6670, p. 904, doi. 10.1038/36122
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- Publication type:
- Article
Tracing the network connecting BRCA and Fanconi anaemia proteins.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the α chain of the interleukin-7 receptor.
- Published in:
- European Journal of Immunology, 1994, v. 24, n. 9, p. 2168, doi. 10.1002/eji.1830240935
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- Publication type:
- Article
A phenotypically dominant regulatory mechanism suppresses major histocompatibility complex class II gene expression in a murine plasmacytoma.
- Published in:
- European Journal of Immunology, 1987, v. 17, n. 10, p. 1441, doi. 10.1002/eji.1830171009
- By:
- Publication type:
- Article
From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1.
- Published in:
- Angewandte Chemie International Edition, 2011, v. 50, n. 17, p. 4003, doi. 10.1002/anie.201008019
- By:
- Publication type:
- Article
Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation.
- Published in:
- Molecular Oncology, 2014, v. 8, n. 2, p. 161, doi. 10.1016/j.molonc.2013.10.005
- By:
- Publication type:
- Article