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- Title
A review of spontaneous intracranial extradural hematoma in sickle-cell disease.
- Authors
Hettige, Samantha; Sofela, Agbolahan; Bassi, Sanj; Chandler, Chris
- Abstract
Sickle-cell disease is common among patients of Afro-Caribbean origin. Though it can precipitate neurological conditions, it only rarely causes neurosurgical problems, with very few reported cases. We describe the case of a 7-year-old girl with a background of sickle-cell disease (SCD) brought into an acute neurosurgical unit in extremis, signs of a raised ICP, and with no history of recent trauma. Following further investigations, an acute drop in the hemoglobin and hematocrit levels were noted, with the cause of her presentation being attributed to a sickling crisis causing skull convexity infarction and resulting in spontaneous bilateral extradural hematomas requiring emergency evacuation. We review the current literature and propose the pathophysiological mechanism behind this phenomenon.
- Subjects
SICKLE cell anemia; EPIDURAL hematoma; INFARCTION; NEUROLOGICAL nursing; HEMOGLOBINS; HEMATOCRIT
- Publication
Acta Neurochirurgica, 2015, Vol 157, Issue 11, p2025
- ISSN
0001-6268
- Publication type
Article
- DOI
10.1007/s00701-015-2582-6